Browsing by Autor "Alba Inchausti"

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    Leishmanicidal and Trypanocidal activities of Acetogenins isolated fromAnnona glauca
    (Wiley, 1998) Anne-Isabelle Waechter; Gloria Yaluff; Alba Inchausti; Antonieta Rojas de Árias; Reynald Hocquemiller; André Cavé; Alain Fournet
    The dichloromethane extract of seeds of Annona glauca (Annonaceae) was active against three strains of Leishmania species. Nine known acetogenins were isolated and identified and then evaluated in vitro against Leishmania species and the bloodstream forms of Trypanosoma cruzi. Annonacin A and goniothalamicin showed activity against Leishmania, and glaucanisin, squamocin, annonacin A and annonacin against Trypanosoma cruzi reducing the parasites by 78%, 67%, 71% and 85%, respectively. Copyright © 1998 John Wiley & Sons, Ltd.