Browsing by Autor "Alejandro Garay"

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Diseño conceptual de jardín botánico “Palmetum del Mundo” en los Emiratos Árabes Unidos
(2020) Alejandro Garay; A P Jorge Durán; Lino Valera; Vicente Garay Jerez; Luis E. Gámez; María Belkis Durán; Julio Quintero; Axel Atilio Contreras Owen
Landscaping is an area of professional knowledge that currently warrants its recognition and a higher profile in the planning and management of a natural and urban territory, especially in industrial developing countries. Venezuela needs a higher number of specialists in this area with academic and practical training, however, only the Faculty of Architecture and Urbanism of the Central University of Venezuela, offers appropriate courses within its wide range of undergraduate, specialization and master's degrees. Given that the Faculty of Forestry and Environmental Sciences of the University of Los Andes, is the only one of its kind in the country and has more than sixty years of history, in addition to a multiplicity of experts in the different areas of science and technology in the forestry and environmental sector, a course on Landscaping and Arboriculture was recently created within the Department of Forests of the School of Forest Engineering of the aforementioned institution. This will lay the methodological foundations, as well as the integration and exchange of knowledge between different highly qualified professionals in the areas of urban planning, architecture, forestry, civil engineering, among others. It is a hope for the future to increase the possibilities of employment of these professionals graduating from the University of Los Andes and, with it, promoting the creation of specialized private companies that manage and improve the urban landscape of Venezuelan cities. In the cities, the road networks, parks, squares, residential developments, hotels and businesses, among others, lack good landscaping and arboriculture initiatives. Therefore, in order to integrate the knowledge of the academics involved, it was agreed to initiate the conceptual academic work of the landscaping and arboriculture subject with the development of a proposal for the Botanical Garden Palmetum of the World in the United Arab Emirates, which is an example of urban and architectural development, with cities like Abu Dhabi and Dubai, and where impressive tourist infrastructures of a unique nature have been built.
El diseño ambientalmente integrado y el ecodiseño en la elaboración de tableros aglomerados de partículas de Bambú con adhesivo fenol formaldehido.
(2010) Wilver Contreras Miranda; Styles W. Valero; Mary E. Owen de Contreras; B Vicente Cloquell; María Teresa Rondón Sulbarán; Eric Barrios; Alejandro Garay; Ángel Segundo Contreras
Legionella pneumophila is a facultative intracellular pathogen which readily grows in human and guinea pig macrophages and in peritoneal exudate macrophages from A/J mice. Macrophage cultures capable of supporting the growth of Legionella can be used to test the potency of biologically active substances suspected of modulating host mechanisms of resistance to infection. Accordingly, this model was used to evaluate the influence of delta-9-tetrahydro-cannabinol (THC) on macrophage resistance to infection with an intracellular pathogen. Pretreatment of the macrophages with THC in the concentration range of 2.5 micrograms/ml (8 microM) to 5.0 micrograms/ml (16 microM) had little if any effect on the ability of the macrophages to either ingest or support the replication of Legionella. However, THC treatment of cells following Legionella infection resulted in increased numbers of bacteria recoverable from the macrophage cultures. Stimulation of the macrophage cultures with the activating agent lipopolysaccharide (LPS) was effective in reducing the ability of Legionella to grow in the cells. However, treatment of the LPS activated macrophages with THC resulted in greater growth of the Legionella in the cultures, indicating that the drug abolished the LPS induced enhanced resistance. These results demonstrate that THC treatment of macrophages following infection rather than before infection with Legionella promotes the replication of the bacteria within the macrophages. In addition, drug treatment suppresses the growth restricting potential of macrophages activated by LPS.