Browsing by Autor "Alexandra Schwarz"

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An Updated Insight into the Sialotranscriptome of Triatoma infestans: Developmental Stage and Geographic Variations
(Public Library of Science, 2014) Alexandra Schwarz; Nora Medrano-Mercado; Günter A. Schaub; Claúdio J. Struchiner; M. Dolores Bargues; Michael Z. Levy; José M. C. Ribeiro
Over five thousand CDS, mostly full length or near full length, were publicly deposited on GenBank. Transcripts that were over 10-fold overexpressed from different geographical regions, or from different developmental stages were identified. Polymorphisms were mapped to derived coding sequences, and found to vary between developmental instars and geographic origin of the biological material. This expanded sialome database from T. infestans should be of assistance in future proteomic work attempting to identify salivary proteins that might be used as epidemiological markers of vector exposure, or proteins of pharmacological interest.
Antibody responses of domestic animals to salivary antigens of Triatoma infestans as biomarkers for low-level infestation of triatomines
(Elsevier BV, 2009) Alexandra Schwarz; J. Sternberg; Valerie Johnston; Nora Medrano-Mercado; Jennifer M. Anderson; Jen C. C. Hume; Jesús G. Valenzuela; Günter A. Schaub; Peter F. Billingsley
IgM-antibody responses of chickens to salivary antigens of Triatoma infestans as early biomarkers for low-level infestation of triatomines
(Elsevier BV, 2010) Alexandra Schwarz; Nora Medrano-Mercado; Peter F. Billingsley; Günter A. Schaub; J. Sternberg
Immunogenic Salivary Proteins of Triatoma infestans: Development of a Recombinant Antigen for the Detection of Low-Level Infestation of Triatomines
(Public Library of Science, 2009) Alexandra Schwarz; Stefan Helling; Nicolas Collin; Clarissa Teixeira; Nora Medrano-Mercado; Jen C. C. Hume; Teresa C. F. Assumpção; Katrin Marcus; Christoph Stephan; Helmut E. Meyer
The recombinant rTiSP14.6 is a suitable and promising epidemiological marker for detecting the presence of small numbers of different species of triatomines and could be developed for use as a new tool in surveillance programs, especially to corroborate vector elimination in Chagas disease vector control campaigns.