Browsing by Autor "Alfredo Bruno"

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    Genomic surveillance of SARS-CoV-2 in the Andean Community (2020–2024): integrating regional sequencing efforts from Colombia, Ecuador, Peru, and Bolivia through “ORAS-CONHU” program
    (Frontiers Media, 2025) Alfredo Bruno; Doménica de Mora; Paola Rojas-Estévez; Héctor Alejandro Ruiz-Moreno; Jessica Guzman-Otazo; Omar Cáceres; Verónica Sambra; Jimmy Garcés; Maritza Olmedo; Carlos Franco-Muñoz
    While each country exhibits some specific characteristics, the phylogenetic analysis underscored a common pattern in the lineage evolution of SARS-CoV-2 in the Andean Community supporting a rapid transnational transmission of the virus. This study was part of a regional effort to develop an integrative transnational genomic surveillance network for SARS-CoV-2 as a proxy for a more ambitious regional infectious diseases genomic surveillance program.
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    Patterns of influenza B circulation in Latin America and the Caribbean, 2010–2017
    (Public Library of Science, 2019) Rakhee Palekar; Angel Rodríguez; Cinthia Avila; Gisela Badillo Barrera; Miriam Barrera; Hebleen Brenes; Alfredo Bruno; Nathalie El Omeiri; Rodrigo Fasce; Walquiria Ferreira de Almeida
    Influenza B is important in LAC with both B/Victoria and B/Yamagata circulating annually in all sub regions. During approximately one-third of the seasons, an influenza B vaccine mismatch was identified. Further analyses are needed to better characterize the medical and economic burden of each influenza B lineage, to examine the potential cross-protection of one vaccine lineage against the other circulating virus lineage, and to determine the potential impact and cost-effectiveness of using the quadrivalent vaccine rather than the trivalent influenza vaccine.