Browsing by Autor "Asmiria Sotolongo"

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Características fenotípicas de células T linfocitarias de tipo regulador (Treg) presentes en el hígado de pacientes con infección crónica por VHB
(Universidad Internacional de La Rioja, 2012) Danely Velázquez; Melise Milano; Pierina Petrosino Tepedino; Asmiria Sotolongo; Luisa Barboza; Siham Salmen; Lisbeth Berrueta Carrillo
Hepatitis B virus (HBV) is responsible for irreversible liver damage. In this study we evaluated regulatory T cell that infiltrate the liver in hepatic biopsies from subjects with chronic HBV infection. Data showed a significant increase (p <0.05) in the number of CD4 + T cells co-expressing FoxP3, IL-10 or TGFâ, in HBV chronically infected patients, as compared with the other group of patients. This increase was positively correlated with plasma ALT levels (R= 0.9, p <0.05). There were not significant differences between the clinical groups, when liver infiltrating CD8 + populations were evaluated. These findings may contribute to understand events leading to failure of the immune response associated with recruitment of suppressor-type populations, which could inhibit specific immune response against HBV, therefore contributing to viral persistence.
Higroma quístico fetal: Reporte de un caso
(2003) Lenin Montilla; Pierina Petrosino; Asmiria Sotolongo; María Luisa de Uzcátegui; Franklin Moreno; Julieta de Castillo
Tumor sólido pseudopapilar de páncreas. Presentación de un caso reportado en Hospital Universitario de Los Andes, Mérida-Venezuela
(Universidad de Los Andes, 2013) Naisbet Ortega Vásquez; Melisse Milano Molina; Ana Valentina Rojas-Esquerre; Estrella Celeste Uzcátegui Paz; Carlos González Torres; Pierina Petrosino Tepedino; Asmiria Sotolongo; Elymar Barreto; Julio Tabares
El tumor solido pseudopapilar de pancreas es una neoplasia de bajo grado de malignidad, de etiologia incierta y relativamente raro con una incidencia de 0.2 a 2.7% entre los tumores de pancreas exocrino. Se presenta con mayor frecuencia en mujeres jovenes, siendo muy raro en varones, y existen pocos casos de mortalidad asociados a este tumor. Pueden encontrarse incidentalmente o dar sintomas abdominales inespecificos. Presentamos el caso de paciente femenina de 16 anos de edad, quien consulto por saciedad temprana y dolor abdominal tipo colico en epigastrio e hipocondrio derecho. Se realizo endoscopia digestiva superior puncion con aguja guiada (PAF) guiada por ultrasonido endoscopico de lesion quistica en cola de pancreas, con hallazgos compatibles con tumor solido pseudopapilar de pancreas. Se realizo Pancreatectomia corporo-caudal con estudio de biopsia, los cuales confirmaron el diagnostico preoperatorio. El tumor solido pseudopapilar pancreatico incluye entre sus manifestaciones clinicas dolor abdominal, sensacion de plenitud o saciedad temprana, masa abdominal, nauseas y vomitos, entre otras. La tomografia axial computarizada puede revelar masa heterogenea grande y encapsulada. El diagnostico definitivo se realiza con el estudio histopatologico y el tratamiento de eleccion es la cirugia, la cual por si sola tiene un nivel elevado de curacion. Solid-pseudopapillary tumor of the pancreas. A report in the Hospital Universitario de Los Andes, Merida-Venezuela Abstract Solid pseudopapillary tumor of the pancreas is a neoplasm of low malignant, of uncertain etiology and relatively rare with an incidence of 0.2 to 2.7% between exocrine pancreatic tumors. It occurs most often in young women and is very rare in men, and there are few cases of mortality associated with this tumor. May be found incidentally or give nonspecific abdominal symptoms. We report the case of a female patient aged 16, who consulted with early satiety and cramping abdominal pain in epigastrium and right hypochondrium. Upper gastrointestinal endoscopy was performed and a endoscopic ultrasound guided fine needle aspiration of the cystic lesiom was performed, with findings consistent with pancreatic solid pseudopapillary tumor. Pancreatectomy was performed porated-flow with biopsy study, which confirmed the preoperative diagnosis. Solid pseudopapillary tumor pancreatic includes among its clinical manifestations abdominal pain, fullness or early satiety, abdominal mass, nausea and vomiting, among others. Computed tomography may reveal large encapsulated heterogeneous mass. The definitive diagnosis is made by histological study and treatment of choice is surgery, which alone has a high level of healing.