Browsing by Autor "Camila Diedrich"

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    Adequacy of food consumption in elderly Alzheimer’s disease in a community of Southern Brazil: a Cross-sectional study
    (Faculty of 1000, 2018) Gláucia Renée Hilgemberg; Aline Jacoski de Oliveira Krüger da Silva; Bárbara Luísa Fermino; Camila Diedrich; Simone Carla Benincá; Débora Fernandes Pinheiro; Flávia Ivanski; Fernando Sluchensci dos Santos; Weber Cláudio Francisco Nunes da Silva; Caryna Eurich Mazur
    <ns4:p> <ns4:bold>Background:</ns4:bold> Alzheimer's disease (AD) is the most common cause of dementia, with a multifactorial etiology, in which the person has great difficulty identifying feelings of hunger, satiety, and feeding, which may affect their nutritional status. Pathologically, it is associated with neurodegeneration of synapses followed by neuronal loss, accompanied by glial proliferation surrounded by neurofibrillary tangles, beta-amyloid peptide (Aβ) deposition, inflammation and cerebrovascular injury hindering the ability to perform activities of daily living. This study aimed to analyze quantitatively the differences between an elderly group with AD and a control group, in terms of macro and micronutrient consumption evaluation. </ns4:p> <ns4:p> <ns4:bold>Methods:</ns4:bold> the study involved 69 participants who were assessed via collection of anthropometric measurements (weight, height and body mass index) with nutritional status being assessed by 24-hour food recall and three-day food record. Cognitive assessments were performed using the Mini-Mental State Examination (MMSE) and Clinical Dementia Ranting (CDR). </ns4:p> <ns4:p> <ns4:bold>Results:</ns4:bold> The intake of lipids in patients with severe dementia, was lower (p &lt;0.05). The consumption of proteins showed a decrease with demential advance. For vitamins, there was a significant difference (p &lt;0.05) in the amount of thiamine, niacin, vitamin D, E and K and calcium, chromium and iodine minerals, which were significantly reduced in AD patients (p &lt;0.05). </ns4:p> <ns4:p> <ns4:bold>Conclusions:</ns4:bold> Decreases in macronutrient and micronutrient consumption may result in a consequent impairment of nutritional status, dementia progression, and decreased quality and life expectancy of elderly patients with AD. </ns4:p>