Browsing by Autor "Carmen Revollo"

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HELICOBACTER PYLORI SERO-INCIDENCE IN A COHORT OF RURAL BOLIVIAN CHILDREN
(Lippincott Williams & Wilkins, 1998) C Friedman; Mike Glynn; Robert Quick; B Khanna; Naomi Iihoshi; Carmen Revollo; B. D. Gold
58 High seroprevalence rates for Helicobacter pylori (Hp) have been reported in developing countries; however, sero-incidence studies to determine age of initial acquisition and risk factors for seroconversion are lacking. We conducted two seroprevalence studies, 15 months apart, to determine the age-specific sero-incidence rate in a cohort of rural Bolivian children. In 8/96, we conducted a survey of 1,392 children between 6 months and 9 years old, living in 17 rural Bolivian villages, to determine Hp serostatus. In 11/97, we returned to the same villages to conduct a follow-up study. The 15 month age-specific sero-incidence was determined for a cohort of 333 children, 6 months and 6 years old, who either participated in both surveys and were seronegative in the first or were born during the follow-up period. Overall, 36% of 1040 children surveyed in the follow-up study were seropositive, 52% were seronegative, and 12% had indeterminate serostatus. Of 918 children with a definitive Hp serostatus, seroprevalence increased from 4% in children aged 6-11 months to 61% in 6-year olds. In the cohort of 333 children, 64 (19%) seroconverted during the 15 month follow-up period. 15-month sero-incidence rates are summarized in the table below: The largest increase in sero-incidence occurred in children between ages 2 and 3 years old. Further analysis of risk factors for Hp seroconversion (i.e., infection acquisition) focusing on this age group is ongoing.TABLE
<i>HELICOBACTER PYLORI</i> SERO‐INCIDENCE IN A COHORT OF RURAL BOLIVIAN CHILDREN
(Lippincott Williams & Wilkins, 1998) C Friedman; Mike Glynn; Robert Quick; B Khanna; Naomi Iihoshi; Carmen Revollo; B. D. Gold
Relevant increase of CTX-M-producing Escherichia coli carriage in school-aged children from rural areas of the Bolivian Chaco in a three-year period
(Elsevier BV, 2022) Selene Rebecca Boncompagni; Maria Micieli; Tiziana Di Maggio; Antonia Mantella; Anna Liz Villagrán; Tatiana Briggesth Miranda; Carmen Revollo; Veronica Poma; Herlan Gamboa; Michele Spinicci
Seroincidence of<i>Helicobacter pylori</i>Infection in a Cohort of Rural Bolivian Children: Acquisition and Analysis of Possible Risk Factors
(Oxford University Press, 2002) M. Kathleen Glynn; Cindy R. Friedman; Benjamin D. Gold; Bhawna Khanna; Lori Hutwagner; Naomi Iihoshi; Carmen Revollo; Robert Quick
High seroprevalence rates for Helicobacter pylori are reported in developing countries, yet few seroincidence studies exist that determine age of initial acquisition and risk factors for H. pylori seroconversion. Two H. pylori serosurveys were conducted in August 1996 and November 1997. Of 188 children aged 21 months to 6 years who were seronegative in the first survey, 44 (23%) had seroconverted at follow-up, yielding an 18% annual seroincidence. The largest increase in seroincidence occurred between children aged 2 years (10%) and children aged 3 years (32%). Use of a lidded, narrow-mouthed water vessel was protective against seroconversion (odds ratio [OR], 0.3; 95% confidence interval [CI], 0.1-0.8), and the presence of another H. pylori-seropositive sibling in the household was a risk factor for seroconversion (OR, 3.1; 95% CI, 1.3-8.7). Although not a randomized intervention trial, this study suggests that the use of a narrow-mouthed water vessel may prevent the transmission of H. pylori in households in developing countries.