Browsing by Autor "Cristo A Carrasco Mendoza"

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    A randomized trial of amphotericin B alone or in combination with itraconazole in the treatment of mucocutaneous leishmaniasis
    (Instituto Oswaldo Cruz, Ministério da Saúde, 1995) Luis Valda Rodriguez; Jean-Pierre Dedet; Virginia Paredtes; Cristo A Carrasco Mendoza; Fernando Cárdenas
    A randomized trial of amphotericin B (AB) alone and in combination with oral itraconazole (IZ) is carried out in two groups of 10 mucocutaneous leishmaniasis patients from Bolivia and Peru. AB+IZ combination is no better than AB monotherapy, as far as efficacy and tolerability are concerned. No antagonism was detected.
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    Electrocardiographic alterations during treatment of mucocutaneous leishmaniasis with meglumine antimoniate and allopurinol
    (Oxford University Press, 1992) G Antezana; R. Jorge Zeballos; Cristo A Carrasco Mendoza; Philippe Lyèvre; L Valda; Fernando Cárdenas; Irma Noriega; Helena Ugarte; J. P. Dédet
    The electrocardiographic (ECG) changes in Bolivian patients with mucocutaneous leishmaniasis, treated with meglumine antimoniate and allopurinol, were evaluated. Electric changes due to the antimonial compound appeared in 45% of the patients, and consisted of repolarization alteration, principally affecting the T wave and the S-T segment. The changes disappeared within 2 months following the end of the antimonial treatment. In patients with associated Chagas disease and leishmaniasis, antimonial therapy did not aggravate the ECG changes characteristic of Chagasic cardiopathy.