Browsing by Autor "Daniela R. Lacerda"

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A new subhaplogroup of native American Y-Chromosomes from the Andes
(Wiley, 2011) Marilza S. Jota; Daniela R. Lacerda; José R. Sandoval; Pedro Paulo Vieira; Simone S. Santos-Lopes; Rafael Bisso‐Machado; Vanessa Rodrigues Paixão‐Côrtes; Susana Revollo; César Paz‐y‐Miño; Ricardo Fujita
The human Y chromosome contains highly informative markers for making historical inferences about the pre-Columbian peopling of Americas. However, the scarcity of these markers has limited its use in the inference of shared ancestry and past migrations relevant to the origin of the culturally and biologically diverse Native Americans. To identify new single nucleotide polymorphisms (SNPs) and increase the phylogenetic resolution of the major haplogroup Q found in the Americas, we have performed a search for new polymorphisms based on sequencing divergent Y chromosomes identified by microsatellite haplotype analysis. Using this approach, a new Y-SNP (SA01) has been identified in the Andean populations of South America, allowing for the detection of a new sublineage of Q1a3a. This sublineage displays a less complex phylogeographic network of associated microsatellites and more restricted geographic occurrence, and is given the designation Q1a3a4. This result indicates that our approach can be successfully used to identify sublineages of interest in a specific region that allow the investigation of particular histories of human populations.
Genetic ancestry of families of putative Inka descent
(Springer Science+Business Media, 2018) José R. Sandoval; Daniela R. Lacerda; Marilza S. Jota; Ronald Elward; Óscar Acosta; Donaldo Pinedo; Pierina Danós; Cinthia Cuellar; Susana Revollo; Fabrício R. Santos
Genetic portrait of the Amazonian communities of Peru and Bolivia: The legacy of the Takanan‐speaking people
(Wiley, 2023) José R. Sandoval; Susana Revollo; Cinthia Cuellar; Daniela R. Lacerda; Marilza S. Jota; Ricardo Fujita; Fabrício R. Santos
During the colonial period in South America, many autochthonous populations were affected by relocation by European missionary reductions and other factors that impacted and reconfigured their genetic makeup. Presently, the descendants of some "reduced" and other isolated groups are distributed in the Amazonian areas of Peru, Bolivia, and Brazil, and among them, speakers of Takanan and Panoan languages. Based on linguistics, these peoples should be closely related, but so far no DNA comparison studies have been conducted to corroborate a genetic relationship. To clarify these questions, we used a set of 15 short tandem repeats of the non-recombining part of the Y-chromosome (Y-STRs) and mitochondrial DNA (mtDNA) control region sequence data. Paternal line comparisons showed the Takanan-speaking peoples from Peru and Bolivia descended from recent common ancestors; one group was related to Arawakan, Jivaroan, and Cocama and the other to Panoan speakers, consistent with linguistics. Also, a genetic affinity for maternal lines was observed between some Takanan speakers and individuals who spoke different Amazonian languages. Our results supported a shared ancestry of Takanan, Panoan, Cocama, and Jivaroan-speaking communities who appeared to be related to each other and came likely from an early Arawak expansion in the western Amazonia of South America.
New native South American Y chromosome lineages
(Springer Nature, 2016) Marilza S. Jota; Daniela R. Lacerda; José R. Sandoval; Pedro Paulo Vieira; Dominique Ohasi; José E Santos-Júnior; Óscar Acosta; Cinthia Cuellar; Susana Revollo; César Paz‐y‐Miño
The Genetic History of Indigenous Populations of the Peruvian and Bolivian Altiplano: The Legacy of the Uros
(Public Library of Science, 2013) José R. Sandoval; Daniela R. Lacerda; Marilza S. Jota; Alberto Salazar‐Granara; Pedro Paulo Vieira; Óscar Acosta; Cinthia Cuellar; Susana Revollo; Ricardo Fujita; Fabrício R. Santos
The Altiplano region of the South American Andes is marked by an inhospitable climate to which the autochthonous human populations adapted and then developed great ancient civilizations, such as the Tiwanaku culture and the Inca Empire. Since pre-Columbian times, different rulers established themselves around the Titicaca and Poopo Lakes. By the time of the arrival of Spaniards, Aymara and Quechua languages were predominant on the Altiplano under the rule of the Incas, although the occurrence of other spoken languages, such as Puquina and Uruquilla, suggests the existence of different ethnic groups in this region. In this study, we focused on the pre-Columbian history of the autochthonous Altiplano populations, particularly the Uros ethnic group, which claims to directly descend from the first settlers of the Andes, and some linguists suggest they might otherwise be related to Arawak speaking groups from the Amazon. Using phylogeographic, population structure and spatial genetic analyses of Y-chromosome and mtDNA data, we inferred the genetic relationships among Uros populations (Los Uros from Peru, Uru-Chipaya and Uru-Poopo from Bolivia), and compared their haplotype profiles with eight Aymara, nine Quechua and two Arawak (Machiguenga and Yanesha) speaking populations from Peru and Bolivia. Our results indicated that Uros populations stand out among the Altiplano populations, while appearing more closely related to the Aymara and Quechua from Lake Titicaca and surrounding regions than to the Amazon Arawaks. Moreover, the Uros populations from Peru and Bolivia are genetically differentiated from each other, indicating a high heterogeneity in this ethnic group. Finally, our results support the distinctive ancestry for the Uros populations of Peru and Bolivia, which are likely derived from ancient Andean lineages that were partially replaced during more recent farming expansion events and the establishment of complex civilizations in the Andes.
Y Chromosome Sequences Reveal a Short Beringian Standstill, Rapid Expansion, and early Population structure of Native American Founders
(Elsevier BV, 2018) Thomaz Pinotti; Anders Bergström; M. Geppert; Matt Bawn; Dominique Ohasi; Wentao Shi; Daniela R. Lacerda; Arne Solli; Jakob Norstedt; Kate Reed
Y Chromosome Sequences Reveal a Short Beringian Standstill, Rapid Expansion, and early Population structure of Native American Founders
(Monash University, 2019) Thomaz Pinotti; Anders Bergström; Maria Seidel; Matt Bawn; Dominique Ohasi; Wentao Shi; Daniela R. Lacerda; Arne Solli; Jakob Norstedt; Kate Reed
The Americas were the last inhabitable continents to be occupied by humans, with a growing multidisciplinary consensus for entry 15-25 thousand years ago (kya) from northeast Asia via the former Beringia land bridge [1-4]. Autosomal DNA analyses have dated the separation of Native American ancestors from the Asian gene pool to 23 kya or later [5, 6] and mtDNA analyses to ∼25 kya [7], followed by isolation ("Beringian Standstill" [8, 9]) for 2.4-9 ky and then a rapid expansion throughout the Americas. Here, we present a calibrated sequence-based analysis of 222 Native American and relevant Eurasian Y chromosomes (24 new) from haplogroups Q and C [10], with four major conclusions. First, we identify three to four independent lineages as autochthonous and likely founders: the major Q-M3 and rarer Q-CTS1780 present throughout the Americas, the very rare C3-MPB373 in South America, and possibly the C3-P39/Z30536 in North America. Second, from the divergence times and Eurasian/American distribution of lineages, we estimate a Beringian Standstill duration of 2.7 ky or 4.6 ky, according to alternative models, and entry south of the ice sheet after 19.5 kya. Third, we describe the star-like expansion of Q-M848 (within Q-M3) starting at 15 kya [11] in the Americas, followed by establishment of substantial spatial structure in South America by 12 kya. Fourth, the deep branches of the Q-CTS1780 lineage present at low frequencies throughout the Americas today [12] may reflect a separate out-of-Beringia dispersal after the melting of the glaciers at the end of the Pleistocene.