Browsing by Autor "Dieter Klemm"

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    Bacterial nanocellulose as a new patch material for closure of ventricular septal defects in a pig model
    (Oxford University Press, 2014) Nora Lang; Elena Merkel; Franziska Fuchs; Dieter Schumann; Dieter Klemm; Friederike Krämer; Susanne Mayer‐Wagner; Christian Schroeder; Franz Freudenthal; Heinrich Netz
    BNC patches can close VSDs with good mid-term results and its biocompatibility can be considered as satisfactory. Its elasticity increases in the presence of blood, which might be advantageous. Therefore, it has potential to be used as an alternative patch material in congenital heart disease.
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    Evaluation of bacterial cellulose as a new patch material for closure of muscular ventricular septal defects
    (Georg Thieme Verlag, 2010) Nora Lang; Matthias Sigler; Elisabeth Merkel; F. Fuchs; Dieter Schumann; Dieter Klemm; Frank Krämer; Andreas Meyer; R Thalmann; Anja Lehner
    Objective: Bacterial Cellulose (BC) is an innovative biomaterial with unique properties such as high mechanical strength, high water content and poor degradation in vivo. The fiber network structures show similarities to those of collagen. Recent studies have shown that the BC might have a potential to be used as a scaffold in tissue engineering. Thus, aim of this study was evaluation of the in vivo biocompatibility of BC in the heart and the applicabilities as a patch material for muscular ventricular septal defects (mVSD).