Browsing by Autor "Dominik T. Schneider"

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    Antibody drop in newborns congenitally infected by<i>Trypanosoma cruzi</i>treated with benznidazole
    (Wiley, 2009) Jean‐Philippe Chippaux; Alejandra N. Salas Clavijo; José Santalla; Jorge R. Postigo; Dominik T. Schneider; Laurent Brutus
    Recovery may be confirmed in most cases at 10 months. The CSP test was compared to Chagatest v3.0 ELISA and appeared to give a reliable response. The decrease rate of antibodies does not depend on treatment modes.
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    Door‐to‐door screening as a strategy for the detection of congenital Chagas disease in rural Bolivia
    (Wiley, 2011) Mario Romero; Jorge Postigo; Dominik T. Schneider; Jean‐Philippe Chippaux; José Santalla; Laurent Brutus
    Despite poorer outcomes after door-to-door screening activities have been transferred to the health system, a combined strategy based on active and passive case detection appeared to be efficient for identifying rural cases of congenital Chagas disease.
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    Epidemiological evaluation of Chagas disease in a rural area of southern Bolivia
    (Oxford University Press, 2008) Jean‐Philippe Chippaux; Jorge R. Postigo; José Santalla; Dominik T. Schneider; Laurent Brutus
    We evaluated the prevalence of Chagas disease using a rapid screening test (Chagas Stat-Pak), confirmed by ELISA, in Caraparí, a village of 9000 inhabitants in southern Bolivian Chaco. The prevalence of Trypanosoma cruzi was estimated in a sample of 995 people. The prevalence adjusted on age was 51.2% and was proportionally related to age. We also observed a very significant cline from the south to the north of the locality, where the prevalence ranged from 40 to 80%. In children younger than 11 years, the prevalence was 21.5%, which confirmed the importance of residual vector transmission despite several years of vector control. Among women of procreation age, the prevalence was 63.9%, resulting in a high risk of congenital transmission. The control of the disease requires an increase in vector control and improvement of dwellings before considering children's treatment with trypanocide.
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    Prevalence of Chagas disease in pregnant women and incidence of congenital transmission in Santa Cruz de la Sierra, Bolivia
    (Elsevier BV, 2012) Nadin A. Salas Clavijo; Jorge R. Postigo; Dominik T. Schneider; José Santalla; Laurent Brutus; Jean‐Philippe Chippaux