Browsing by Autor "Elisabeth Merkel"

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    Evaluation of a self-centering patch system for closure of muscular ventricular septal defects in a pig model
    (Georg Thieme Verlag, 2010) Nora Lang; A Mever; Elisabeth Merkel; R Thalmann; Anja Lehner; Franz Freudenthal; Nikolay V. Vasilyev; Pedro J. del Nido; Heinrich Netz; Rainer Kozlik‐Feldmann
    Objective: Closure of muscular ventricular septal defects (mVSDs) beyond the moderator band is still challenging. Recently, we established a new hybrid technique for closure of mVSDs on the beating heart. Here, we evaluated a self-centering patch system for this technique.
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    Evaluation of bacterial cellulose as a new patch material for closure of muscular ventricular septal defects
    (Georg Thieme Verlag, 2010) Nora Lang; Matthias Sigler; Elisabeth Merkel; F. Fuchs; Dieter Schumann; Dieter Klemm; Frank Krämer; Andreas Meyer; R Thalmann; Anja Lehner
    Objective: Bacterial Cellulose (BC) is an innovative biomaterial with unique properties such as high mechanical strength, high water content and poor degradation in vivo. The fiber network structures show similarities to those of collagen. Recent studies have shown that the BC might have a potential to be used as a scaffold in tissue engineering. Thus, aim of this study was evaluation of the in vivo biocompatibility of BC in the heart and the applicabilities as a patch material for muscular ventricular septal defects (mVSD).