Browsing by Autor "Esperanza Azogue"

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    Congenital Chagas' disease in Bolivia: epidemiological aspects and pathological findings
    (Oxford University Press, 1985) Esperanza Azogue; C. La Fuente; Ch. Darras
    In 329 newborns examined by the method of Strout and/or histopathological sections of the placenta, Trypanosoma cruzi was observed in 25 cases. The serological prevalence of Chagas' disease in mothers was 51%. A greater risk of congenital transmission was observed in newborns ranging between 1,001 and 2,500 g (21%), compared to 2% in newborns weighing more than 2,500 g. Congenital transmission occurred predominantly in newborns with a gestational age of 26 to 37 weeks. Histopathological examination of placentae disclosed T. cruzi in 6 ·3%. In areas with a high prevalence of Chagas' disease, congenital transmission is a real hazard.
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    Estúdio prospectivo de la enfermedad de chagas en recien nacidos con infección placent aria por Trypanosoma cruzi (Santa Cruz-Bolivia)
    (Brazilian Society of Tropical Medicine, 1991) Esperanza Azogue; Christian Darras
    In order to know the significance of placental infection by T. cruzi 820 newborn infants (NB) weighing less than or equal to 2500 grs were examined both clinically and by the Strout method and histopathological sections of the placenta in order to detect congenital infection with Chagas' disease. Thirty five (4.26%) NB presented a placentary infections by T. cruzi, but having a negative direct parasitological examination in the cord blood, these NB were followed up parasitologically (microhematocrit), in order to detect an eventual positive change in the post-partum period. The follow-up was done at 7, 15, 30 and 60 days after birth, and with xenodiagnosis 15 days later. In 27 newborn (3.29%) it was possible to complete their follow-up with detection of T. cruzi in every case. In the control group, constituted by NB which were negative to both methods, there was no positivisation at all during the follow-up period. These observations show a high frequency of congenital T. cruzi infection in Santa Cruz.
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