Browsing by Autor "Flavia-Laura Barbieri"

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Child neurodevelopment in a Bolivian mining city
(Elsevier BV, 2011) María Ruiz‐Castell; Pamela Paco; Flavia-Laura Barbieri; Jean‐Louis Duprey; Joan Forns; Anne‐Elie Carsin; Rémi Freydier; Corinne Casiot; Jordi Sunyer; Jacques Gardon
CHILD NEURODEVELOPMENT IN A BOLIVIAN MINING CITY
(National Institute of Environmental Health Sciences, 2011) María Ruiz‐Castell; Pamela Paco; Flavia-Laura Barbieri; Jean‐Louis Duprey; Joan Forns; Anne-Elie Carsina; Rémi Freydier; Corinne Casiot; Jordi Sunyer; Jacques Gardon
Background and Aims: This study evaluates the neurodevelopment of children living near highly contaminated mining industries during their first year of life. Methods: Participants from the city of Oruro (Bolivia) were prospectively recruited during pregnancy and followed-up between May 2007 and November 2009. Questionnaires were used to obtain information regarding the pregnant women’s socioeconomic status, as well as anamnesis. Neurodevelopment was tested on 246 children using the Bayley Scales of Infant Development (BSID) at 10.5 to 12.5 months of age. Trace elements (Pb, As, Cd, Sb, Cs, Zn, Fe, Cu, Se, Rb, Sr) exposure during prenatal life was evaluated by testing maternal blood concentrations before delivery. Results: The blood lead concentration of pregnant women was low, considering the contaminated environmental context. The geometric mean was 1.85µg/dL (95% IC: 1.71; 2.00), a level almost comparable with those observed in non contaminated areas. The only element found to be relatively elevated was antimony, with 1.03µg/dL (95% IC: 0.94; 1.13). The Bayley Scales of Infant Development (BSID) did not reveal mental or psychomotor abnormalities associated to blood levels of trace metals during pregnancy. Almost all levels were lower than the control limits. Conclusion: Our results suggest that women from this mining area were poorly exposed.
Child patterns of growth delay and cognitive development in a bolivian mining city
(Wiley, 2012) María Ruiz‐Castell; Anne‐Elie Carsin; Flavia-Laura Barbieri; Pamela Paco; Jacques Gardon; Jordi Sunyer
In this Bolivian cohort, children born smaller were more likely to grow/develop faster and attain greater weight and length. Their cognitive development was not affected by their growth patterns.