Browsing by Autor "Francisco Bustamante"

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Programas de prevención del suicidio adolescente en establecimientos escolares: una revisión de la literatura
(2013) Francisco Bustamante; Ramón Florenzano U
Las muertes por suicidio han aumentado a nivel mundial y especialmente en nuestro país en la última década. Por ello se hace necesario realizar un trabajo preventivo, principalmente en adolescentes. El presente trabajo tuvo como objetivo realizar una revisión de la literatura de los programas de prevención de suicidio en adolescentes escolares. Los resultados demostraron que son pocos los programas centrados en abordar el suicidio como objetivo principal sino que su foco son factores asociados, como por ejemplo la depresión mayor. Aún así, varios consiguen una disminución de la ideación y conducta suicida en la población estudiada, especialmente cuando implementan más de una intervención.
The Chilean exposome-based system for ecosystems project: Protocol for the development of an informatics platform for national data integration
(Research Square (United States), 2024) Patricia Matus; Alejandro Sepúlveda-Peñaloza; Keneth Page; Claudia Rodríguez; Marcela Cárcamo; Francisco Bustamante; Marcela Garrido; Cinthya Urquidi
Abstract The double burden of diseases and scarce resources in developing countries highlight the need to change conceptualization of health problems and development of translational research. Contrary to the traditional paradigm focused on genetics, the exposome approach proposed in 2005 that complements the genome is an innovative theory. It involves a holistic approach to understanding the complexity of the interactions between the human being’s environment throughout their life and health. Herein, we have describe the conceptual model and technological system development of the Chilean exposome-based system for ecosystems (CHiESS). It is an intelligent and dynamic system for human exposome research, which leverages available administrative data routinely collected by national agencies, in clinical records, and by biobanks. Based on the ecological theory and one-health ecosystem approach, CHiESS considers a multilevel exposure for exposome operationalization, including the ecosystem, community, population, and individual levels. CHiESS will include four consecutive stages for development into an informatic platform: 1) environmental data integration and harmonization system, 2) clinical and omics data integration, 3) advanced analytical algorithm development, and 4) visualization interface development and targeted population-based cohort recruitment. The ChiESS platform aims to integrate and harmonize available secondary administrative data and provide a complete geospatial mapping of the external exposome. Additionally, it aims to analyze complex interactions between environmental stressors of the ecosystem and molecular processes of the human being and their effect on human health. Moreover, by identifying exosome-based hotspots, CHiESS allows the targeted and efficient recruitment of population-based cohorts for translational research and impact evaluation.
Trastorno por déficit atencional con hiperactividad en adultos
(Q16635223, 2003) Arturo Roizblatt S; Francisco Bustamante; Félix Bacigalupo
The attention deficit hyperactivity disorder (ADHD) is the most common diagnosis in child psychiatry, and persists very often in adulthood. These patients have poor lifestyles, especially in affective, work and social areas. Although patients with ADHD have a high rate of comorbidity (e.g. drug and alcohol abuse, depressive and anxiety disorders), this diagnosis is missed by the general physician, deferring its identification and opportune treatment. This article is a review about this disorder and gives tools for its recognition and derivation.