Browsing by Autor "Gabriela Arata de Bellabarba"

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Factores de riesgo para sindrome metabólico en pacientes con higado graso
(2008) Lilia Uzcátegui; José Ángel; Dasyl Martínez; Roald Gómez Pérez; Gabriela Arata de Bellabarba
Se describen, en una serie clinica, los antecedentes personales y familiares de pacientes con diagnostico de higado graso no alcoholico (NAFLD) por ultrasonido (US) y biopsia hepatica. Se seleccionaron 22 historias clinicas, 11 masculinos y 11 femeninos. Se recolectaron los datos en un formulario disenado para tal fin. Se les aplico la clasificacion internacional de NAFLD tanto para el US, como para la biopsia hepatica. Se agruparon los casos por grupos de edad y sexo, para describir las caracteristicas clinicas, perfil bioquimico, hallazgos del US y biopsia. Los resultados son: edad media de 45,8 (27-63 anos), el grupo de edad con mayor porcentaje de casos fue el de 35 a 44 anos Los antecedentes personales para sindrome metabolico (SM), se presentaron en el 90,91% de los casos. Antecedentes familiares relacionados con SM, en 16 pacientes (73 %). El 73 % de los casos tenian sobrepeso u obesidad (por IMC), el 45,45% eran hipertensos. El perfil bioquimico sin alteraciones significativas, al comparar ambos sexos, La mitad de los casos tenian transaminasas normales, trigliceridos elevados en el 45,45 % de los casos, la dislipidemia mixta fue hallada en el 90,91 % del total. El US y la biopsia hepatica reportaron mayor numero de casos para los grados 1 y 2. La interrelacion del US vs biopsia, demostro que el US no evalua los diversos grados de severidad. La interrelacion de los grados de biopsia con las caracteristicas clinicas y perfil lipidico, demostro para el grado 2 por biopsia, valores mas altos para IMC; ALT, trigliceridos y colesterol estadisticamente significativo. La NAFLD se relaciono con SM, el US es util para diagnosticar NAFLD, mas no para definir los grados de severidad, la biopsia hepatica es el metodo para confirmar diagnostico y estudiar la severidad. Se debe sospechar NAFLD en pacientes con factores de riesgo para SM.
Función adrenal y metabolismo lipídico en niños asmáticos tratados con budesonida
(Instituto Nacional de Salud Pública, 1999) Mariela Paoli-de Valeri; Yajaira Zerpa-de Miliani; Ezio G. Valeri-Dávila; Gabriela Arata de Bellabarba
Treatment of asthmatic children with low doses of inhaled budesonide did not modify the adrenal axis function nor lipid metabolism. Asthmatic patients showed an atherogenic lipid profile which could increase the risk of cardiovascular disease.
Heart rate changes during the Valsalva maneuver in patients with isolated aortic insufficiency
(Associação Brasileira de Divulgação Científica, 1997) Alexis Navarro; Diego F. Dávila; A Torres; Gabriela Arata de Bellabarba; José H. Donis; Jorge Casado
To determine the possible relationship between left ventricular dilatation and heart rate changes provoked by the Valsalva maneuver (Valsalva ratio), we studied 9 patients with isolated chronic aortic insufficiency. Left ventricular systolic function was assessed by two-dimensional echocardiography and cardiac catheterization. All patients were asymptomatic (functional class I of the New York Heart Association). The left ventricular internal diameters and volumes were significantly increased in all patients. The asymptomatic patients had either normal or slightly depressed ejection fraction (EF > 0.40). The Valsalva ratio of these asymptomatic patients showed no significant correlation with the left ventricular volumes or with the left ventricular ejection fraction. In other words, parasympathetic heart rate control, as expressed by the Valsalva ratio, was normal in the asymptomatic patients with left ventricular dilatation and preserved left ventricular ejection fraction. Therefore, left ventricular dilatation may not be the major mechanism responsible for the abnormal parasympathetic heart rate control of patients with acquired heart disease.
Influencia de la terapia hormonal de reemplazo sobre la concentración plasmática de leptina en mujeres posmenopáusicas
(2001) Kareen Escalante; Carmen Luisa Uzcategui; Vanessa Villarroel; Carmen Zoraida Molina; Elsy Velásquez M; Gabriela Arata de Bellabarba
Mecanismos de control neural cardíaco en la Enfermedad de Chagas. Implicaciones terapéuticas
(1992) F S Diego Dávila; José H. Donis Hernández; M Argenis Torres; María Navas; Gabriela Arata de Bellabarba; Carlos J. Vásquez; R. Rossell; Carlos F. Gottberg; Sardi Galeno; William Madariaga
According to the Neurogenic Theory the progressive dilatation of the cardiac chambers, of chagasic patients, is due to a destruction of the cardiac vagal neurons. However, the results of our investigations indicate that the cardiac parasympathetic abnormalities, described in chronic Chagas' heart disease, are compensatory mechanisms secondary to the progressive ventricular dilatation. Cardiac parasympathetic abnormalities, and a reciprocal sympathetic hyperactivity, are also present in non-chagasic cardiac patients. Modern medical treatment, with sympatholytic drugs, prolongs life and prerevents ventricular dilatation in' these non-chagasic cardiac patients. In Chagas' heart disease the pathophysiology of the cardiac sympathetic system, as well as its therapeutic implications, is unknown.
Preeclampsia y Actividad Simpática en Embarazada a Término. Mérida. Venezuela
(2001) Rosmeris López; Gabriela Arata de Bellabarba; Carmen Zoraida Molina; L Manuel Santos; Vanessa Villarroel
The objective was to study in preeclampsic women the sympathetic activity by the determination of the plasmatic perypheric levels of norepinephrine (NE) in supine and standing position (orthostatic test). It is a prospective, casecontrol study; 44 women with simple pregnancy were evaluated, 22 (group A) with non treated preeclampsy diagnosis, with no diabetes, hypertension (previous to the pregnancy), or renal disease, and 22 healthy pregnants as control (group B). At the beginning ithe NE concentration in supine and standing position, the blood pressure and cardiac frequency were determined. The mean age was 22 ± 5 years; the pregnancy time was 38 ± 2 weeks, and two pregnancies. Hypertension was the family disorder in 55 % of the study group and 41 % in group B. The basal systolic and diastolic blood pressures were statistically different in both groups, mean 145/97 mm Hg for group A and 94/67 mm Hg for group B. Mothers cardiac frequencies were not statistically different in both groups. The basal NE levels were 218 pg/ml and 241 pg/ml and in standing position were 274 pg/ml and 297 pg/ml respectively, without statistic significance. Group a showed a bimodal aggregation towards the extremes (n = 9) 126 pg/ml and (n = 13) 328 pg/ml, statiscally different from the control (n = 22) 241 pg/ml. The orsthostatic test answer was 25 % for group A and 23 % for group B, statistically similar but low in relation to non pregnant patients of the same age.