Browsing by Autor "Giampaolo Corti"

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    Seroprevalence of Hepatitis A Virus, Hepatitis E Virus, and Helicobacter pylori in Rural Communities of the Bolivian Chaco, 2013
    (American Society of Tropical Medicine and Hygiene, 2018) Irene Campolmi; Michele Spinicci; David Rojo Mayaregua; Herlan Gamboa Barahona; Antonia Mantella; Yunni Lara; Mimmo Roselli; Marianne Strohmeyer; Giampaolo Corti; Francesco Tolari
    In the Bolivian Chaco, south-east of Bolivia, studies conducted over the past three decades reported hepatitis A virus (HAV) and <i>Helicobacter pylori</i> seroprevalences above 90% and 60%, respectively. Hepatitis E virus (HEV) prevalence was previously found to be 6-7% but is probably an underestimate because of the poor sensitivity of the assays used. In November 2013, we conducted a cross-sectional study of 263 healthy volunteers from two rural communities of the Bolivian Chaco, aiming to reassess HAV, HEV, and <i>H. pylori</i> seroprevalence 10-20 years following the previous surveys. Hepatitis A virus seroprevalence was 95%, with universal exposure after the first decade of life; HEV seroprevalence was considerably higher (31-35%) than that previously reported; <i>H. pylori</i> seroprevalence was 59%, with an age-dependent distribution. The high prevalence of these infections suggests that major efforts are still needed to reduce fecal-oral transmission and to improve human health in the Bolivian Chaco.