Browsing by Autor "Hannah Steinberg"
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Item type: Item , Association of caspase-1 polymorphisms with Chagas cardiomyopathy among individuals in Santa Cruz, Bolivia(Brazilian Society of Tropical Medicine, 2017) Katherine Y. Fu; Roxana Zamudio; Jo Henderson-Frost; Alex Almuedo-Riera; Hannah Steinberg; Steven J. Clipman; Gustavo Duran; Rachel Marcus; Thomas Crawford; Daniel AlyeshCaspase-1 polymorphisms may play a role in Chagas cardiomyopathy development and could serve as markers to identify individuals at higher risk for priority treatment.Item type: Item , Mass spectrometry-based discovery and diagnostic validation of T. cruzi antigens in the urine of congenitally infected Chagas Disease patients(Public Library of Science, 2025) Kathryn Cassels; Raghad Almofeez; Jessica Roman; Hannah Steinberg; Ahana Byne; Amanda Haymond; Freddy Tinajeros; María del Carmen Menduiña; Edith Málaga; Manuela VerásteguiOur work suggests that it is possible to detect Trypanosoma cruzi infection directly from a noninvasively collected fluid such as urine. A direct test in urine with this success rate would be well suited for rapid diagnosis in low-resource areas. Further studies to validate this approach are warranted.