Browsing by Autor "I. Gina Rojas"

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    Antimalarial Activity and Cytotoxicity of (-)-Roemrefidine Isolated from the Stem Bark of<i>Sparattanthelium amazonum</i>
    (Thieme Medical Publishers (Germany), 1999) Verónica Francisca Loewe Muñoz; Michel Sauvain; Patricia Mollinedo; Jorgia Callapa; I. Gina Rojas; A. Giménez; Alexis Valentin; M. Mallié
    (-)-Roemrefidine, an aporphine alkaloid isolated from Sparattanthelium amazonum Martius (Hernandiaceae) a vine from Bolivia, has been found to be active against both resistant and sensitive strains of Plasmodium falciparum in vitro and against P. berghei in mice. The compound demonstrated no cytotoxic activity against three cell lines (KB, HEp-2 and HeLa).