Browsing by Autor "Jacques Berger"

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Change in body water distribution index in infants who become stunted between 4 and 18 months of age
(Springer Nature, 2003) Agnès Gartner; Jacques Berger; Kirsten Simondon; B. Maire; Pierre Traissac; Christopher Ly; José Luís San Miguel; François Simondon; Francis Delpeuch
Definition and Prevalence of Anemia in Bolivian Women of Childbearing Age Living at High Altitudes: The Effect of Iron-Folate Supplementation
(Oxford University Press, 2009) Jacques Berger; Víctor M. Aguayo; José Luís San Miguel; C. Lujan; Wilma Téllez; Pierre Traissac
This paper discusses the effect that high altitudes have on iron metabolism and summarizes the results of an iron-folate supplementation trial. The two main objectives of the trial were to determine hemoglobin cut-off values for the diagnosis of anemia in Bolivian women of childbearing age living at high altitudes, and to estimate the prevalence of anemia in this population. The study showed that nutritional anemia is an important public health problem in such populations and that many methods of assessing it lead to an underestimation of prevalence. The cut-off values defined through this study, one of the few iron supplementation trials conducted at high altitudes, confirm the need to establish revised hemoglobin values for the diagnosis of anemia in populations living at high altitudes.
Effect of High Altitude on Protein Metabolism in Bolivian Children
(Mary Ann Liebert, Inc., 2002) José Luís San Miguel; Hilde Spielvogel; Jacques Berger; Mauricio Araoz; C. Lujan; Wilma Téllez; Esperanza Cáceres; Pierre Gachon; J Coudert; B. Beaufrère
In Bolivia, malnutrition in children is a major health problem that may be caused by inadequate protein, energy, and micronutrient intake; exposure to bacterial and parasitic infections; and life in a multistress environment (high altitude, cold, cosmic radiation, low ambient humidity). However, no data on protein absorption and utilization at high altitude were available. Therefore, we evaluated the effect of altitude on protein metabolism in Bolivian children. We measured protein utilization using leucine labeled with a stable isotope ((13)C) in two groups of healthy prepubertal children matched for age. Group 1 (n = 10) was examined at high altitude (HA) in La Paz (3600 m), and group 2 (n = 10) at low altitude (LA) in Santa Cruz (420 m). The nutritional status did not differ between groups but, as was to be expected, the HA group had higher hemoglobin concentration than the LA group. The children consumed casein that was intrinsically labeled with L-(1-(13)C) leucine and expired (13)CO(2) was analyzed. Samples of expired air were measured by isotope ratio mass spectrometer in Clermont-Ferrand. It was found that cumulative leucine oxidation ((13)CO(2)) at 300 min after ingestion was 19.7 +/- 4.9% at HA and 25.2 +/- 3.2% at LA. These results showed that protein absorption and/or utilization is significantly affected by altitude.
Weekly iron supplementation is as effective as 5 day per week iron supplementation in Bolivian school children living at high altitude
(Springer Nature, 1997) Jacques Berger; VM Aguayo; Wilma Téllez; C. Lujan; Pierre Traissac; JL San Miguel