Browsing by Autor "Janine May"

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    Solvent-Induced Chirality in the Hydroboration of Ketones
    (CSIRO Publishing, 2008) Christoph Baldauf; Nina Dickerhof; Stefan H. Hüttenhain; Stefanie Kern; Nancy Krummrich; Friedrich Kruse; Janine May; Melanie Meister; Kristina Müller; Sabine Rauer
    The influence of the systematic variation of chiral solvents and of diverse Lewis acids on the asymmetric induction of the hydroboration of acetophenone has been studied. None of the solvents used could surpass lactic acid methyl ester, and for the Lewis acids, ZnCl2 and ZnI2 showed positive effects on the enantiomeric excess (ee) and the conversion. Also, the effect of the substrate structure was investigated by comparing the conversion and ee of eight different ketones. Apparently, the achievable asymmetric induction was higher with aromatic ketones.