Browsing by Autor "Jennifer Furin"

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    When are uncontrolled trials in TB scientifically and ethically justified: Borrowing wisdom from early AIDS clinical trials
    (Oxford University Press, 2026) Lindsay McKenna; Mike Frick; Valentina Alarcon-Guizado; Geraint Davies; Jennifer Furin; L. Guglielmetti; Norbert Heinrich; Marcus Low; Mariama Mahmoud; V. Mave
    Tuberculosis treatment trials have used various comparison strategies. To inform trial design for novel tuberculosis regimens, we applied an existing framework for evaluating when uncontrolled trials might be justified. We conclude that the conditions are not met for tuberculosis treatment and that uncontrolled phase 3 trials should not be performed.