Browsing by Autor "Jorgia Callapa"
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Item type: Item , A search for natural bioactive compounds in Bolivia through a multidisciplinary approach(Elsevier BV, 2000) Verónica Francisca Loewe Muñoz; Michel Sauvain; Geneviève Bourdy; S Arrázola; Jorgia Callapa; Grace Ruiz; J Choque; Eric DeharoItem type: Item , A search for natural bioactive compounds in Bolivia through a multidisciplinary approach(Elsevier BV, 2000) Verónica Francisca Loewe Muñoz; Michel Sauvain; Geneviève Bourdy; Jorgia Callapa; S. Bergeron; Irma Torres Rojas; José A. Bravo; Luisa Balderrama; B. Ortiz; A. GiménezItem type: Item , Actividad antipalúdica y potenciación de la cloroquina con alcaloides aporfínicos in vitro(2001) Muñoz; Michel Sauvain; André Fournet; Bernard Weniger; A. Valentín; M. Mallié; Jorgia Callapa; Eric Deharo; Pierre‐Marie DuretItem type: Item , Antimalarial Activity and Cytotoxicity of (-)-Roemrefidine Isolated from the Stem Bark of<i>Sparattanthelium amazonum</i>(Thieme Medical Publishers (Germany), 1999) Verónica Francisca Loewe Muñoz; Michel Sauvain; Patricia Mollinedo; Jorgia Callapa; I. Gina Rojas; A. Giménez; Alexis Valentin; M. Mallié(-)-Roemrefidine, an aporphine alkaloid isolated from Sparattanthelium amazonum Martius (Hernandiaceae) a vine from Bolivia, has been found to be active against both resistant and sensitive strains of Plasmodium falciparum in vitro and against P. berghei in mice. The compound demonstrated no cytotoxic activity against three cell lines (KB, HEp-2 and HeLa).Item type: Item , Antimalarial Activity of Alkaloids from Pogonopus tubulosus(Wiley, 1996) Michel Sauvain; Christian Moretti; José-Antonio Bravo; Jorgia Callapa; Victoria Muñoz; E. Ruiz; Bernard Richard; Louisette Le Men‐OlivierThe antimalarial activity of the Bolivian medicinal plant Pogonopus tubulosus (D.C.) Schumann was evaluated by in vitro testing on trophozoite stages of resistant and sensitive strains of Plasmodium falciparum and by in vivo tests on P. berghei and P. vinckei petteri in mice. The bark of this medicinal plant yielded three alkaloids: tubulosine, psychotrine, cephaeline. Tubulosine showed an interesting activity in vitro with an IC50 of 0.006 μg/mL against the sensitive strain of P. falciparum and an IC50 of 0.011 μg/mL against the resistant strain of P. falciparum. This compound had good in vivo antimalarial activity with an ED50 of 0.05 mg/kg/day on P. vinckei petteri strain and an ED50 of 0.45 mg/kg/day on P. berghei.Item type: Item , Antimalarial Activity of Alkaloids fromPogonopus tubulosus(Wiley, 1996) Michel Sauvain; Christian Moretti; José-Antonio Bravo; Jorgia Callapa; Victoria Muñoz; E. Ruiz; Bernard Richard; Louisette Le Men‐OlivierThe antimalarial activity of the Bolivian medicinal plant Pogonopus tubulosus (D.C.) Schumann was evaluated by in vitro testing on trophozoite stages of resistant and sensitive strains of Plasmodium falciparum and by in vivo tests on P. berghei and P. vinckei petteri in mice. The bark of this medicinal plant yielded three alkaloids: tubulosine, psychotrine, cephaeline. Tubulosine showed an interesting activity in vitro with an IC50 of 0.006 μg/mL against the sensitive strain of P. falciparum and an IC50 of 0.011 μg/mL against the resistant strain of P. falciparum. This compound had good in vivo antimalarial activity with an ED50 of 0.05 mg/kg/day on P. vinckei petteri strain and an ED50 of 0.45 mg/kg/day on P. berghei.Item type: Item , Antiplasmodial activity of Aspidosperma indole alkaloids(Elsevier BV, 2002) Anne‐Claire Mitaine‐Offer; Michel Sauvain; Alexis Valentin; Jorgia Callapa; M. Mallié; Monique Zèches-HanrotItem type: Item , Antiprotozoal activities of Colombian plants(Elsevier BV, 2001) Bernard Weniger; Sara M. Robledo; Gabriel Jaime Murillo Arango; Eric Deharo; Raúl Aragón; Victoria Muñoz; Jorgia Callapa; Annelise Lobstein; Robert AntonItem type: Item , Bioactive phenolic glycosides from Amburana cearensis(Elsevier BV, 1999) José A. Bravo B.; Michel Sauvain; Alberto Gimenez T.; Victoria Muñoz O; Jorgia Callapa; Louisette Le Men‐Olivier; Georges Massiot; Catherine LavaudItem type: Item , Estudio epidemiológico, serológico y molecular de la enfermedad de Chagas en la Amazonia boliviana(2018) Jorgia Callapa; Marcelo Linares; Maria Paucara; Yashira Cerruto; Narda Romero; Yajaira Suxo; Mario Soleto; Juan José Nina; German Coaguila; Mayela MatijasevicItem type: Item , The search for natural bioactive compounds through a multidisciplinary approach in Bolivia. Part II. Antimalarial activity of some plants used by Mosetene indians(Elsevier BV, 2000) Verónica Francisca Loewe Muñoz; Michel Sauvain; Geneviève Bourdy; Jorgia Callapa; Irma Torres Rojas; Leidy J Vargas; Antonius Tae; Eric Deharo