Browsing by Autor "K. Suzuki"

Now showing 1 - 5 of 5

Antibody Response to an Anti‐rabies Vaccine in a Dog Population under Field Conditions in Bolivia
(Wiley, 2008) K. Suzuki; Ester Teresa González; G. Ascarrunz; Ariel Loza Vega; M. Pérez; Gonzalo Ruíz-Filippi; L. Rojas; Kristen Clancy Mancilla; J. A. C. Pereira; J. A. Guzmán
Rabies remains an important public health issue in Bolivia, South America. Public concern and fears are most focussed on dogs as the source of rabies. The objective of the present study was to assess immunity of an inactivated suckling mouse brain vaccine against canine rabies used for the official vaccination campaigns under field conditions in an endemic area of rabies in Bolivia. A total of 236 vaccinated and 44 unvaccinated dogs in Santa Cruz de la Sierra, selected using stratified random sampling, were investigated in order to obtain owned dog characteristics and antibody titres against rabies in April 2007. The proportion of vaccinated dogs with an antibody titre exceeded the protection threshold value of 0.5 EU/ml was 58% [95% confidence intervals (CI): 52-65], indicating that vaccination is likely to elicit an antibody response (odds ratio 6.3, 95% CI: 1.2-11.5). The range of geometric mean of antibody titre for vaccinated dogs (0.89 EU/ml; 95% CI: 0.75-1.04) was considered to meet the minimal acceptable level indicating an adequate immune response to the vaccine. However, the titre level was not satisfactory in comparison with the results from other field investigations with inactivated tissue culture vaccines. It is recommended for public health authorities to (1) consider modernizing their vaccine manufacturing method because the level of immunity induced by the current vaccine is comparably low, (2) conduct frequent vaccination campaigns to maintain high levels of vaccination coverage, and (3) actively manage the domestic dog population in the study area, which is largely responsible for rabies maintenance.
Antibody seroprevalences against rabies in dogs vaccinated under field conditions in Bolivia
(Springer Science+Business Media, 2008) K. Suzuki; Marcelo Ricardo Ítalo Pecoraro; Ariel Loza Vega; M. Pérez; Gonzalo Ruíz-Filippi; G. Ascarrunz; L. Rojas; Anabely Estevez; J. A. Guzmán; J. A. C. Pereira
Descriptive spatial and spatio-temporal analysis of the 2000–2005 canine rabies endemic in Santa Cruz de la Sierra, Bolivia
(Elsevier BV, 2007) K. Suzuki; J. A. C. Pereira; Ronald López; G Morales; L. Rojas; Luciano E. Mutinelli; E. Pons
Rabies‐vaccination Coverage and Profiles of the Owned‐dog Population in Santa Cruz de la Sierra, Bolivia
(Wiley, 2008) K. Suzuki; J. A. C. Pereira; Luiz Armando de Medeiros Frias; Ronald López; Luciano E. Mutinelli; E. Pons
The Bolivian government issued a regulation for rabies control in November 2005, owing to increasing the prevalence of dog and human rabies cases in recent years. An assessment of rabies-vaccination coverage and other factors that might influence the success of the on-going vaccination campaign was needed. The objective of this study was to investigate dog rabies vaccination coverage and risk factors associated with dogs being unvaccinated against rabies, and profiles of the owned-dog population in Santa Cruz de la Sierra, Bolivia, where dog rabies was endemic. Mainly due to logistical reasons, the WHO's expanded programme on immunization cluster-survey method was used. The 390 households were included in the study. Information about dog population and management characteristics was obtained for 542 dogs from 301 households. On average, households had 1.4 dogs and 1.8 dogs per dog-owning household (median = 1). The human-to-dog ratio was 4.6 : 1. During the last 1 year prior to the study, of the 539 dogs aged >or=1 month, 463 (85%; 95% CI 79-91; design effect 3.6) were classified as vaccinated. Amongst the study dogs, dogs aged 1-11 months were the higher risk of dogs not being vaccinated (OR = 8.2; 95% CI 4.3-15.6; P < 0.01). Almost two-thirds of the study dogs were allowed to roam freely throughout the day or in part. Community education efforts should address the importance of dog ownership and movement restriction, and the need to vaccinate young dogs.
Seroprevalence Against Bovine Leukaemia Virus in Dairy Cattle in Bolivia
(2010) Ramón López; K. Suzuki; Ester Teresa González; Gotzone Ruiz; Ariel Loza Vega; C. Coca; J. A. C. Pereira; Marcelo Ricardo Ítalo Pecoraro
This study determined seroprevalence against bovine leukaemia virus and investigated the risk factors with the seropositivity of the virus in daily cattle in Bolivia. Ninety-eight farms in five different provinces in Santa Cruz Department were visited to study 1823 daily cattle. Questionnaire interviews, blood sampling and inspection of skin were performed at each study farm. Individual-cattle sera were analysed using the agarose gel immunodiffusion (AGID) diagnostic method for the detection of antibody against bovine leukaemia virus. The overall percentage of test positive against bovine leukaemia virus was 29% (95% confidence interval: 27-31%). One percent of the study daily cattle had the subcutaneous lesions. There were statistical differences for percentage of test positive against bovine leukaemia virus in daily cattle between provinces (p<0.001). The seropositivity in relation to the existence of subcutaneous lesions indicated statistical significance (p = 0.023). Knowledge of the provincial difference of seropositivity against bovine leukaemia virus in daily cattle would be used to determine the resource allocation for preventive measures in the study area. In the preventive measures, serological tests against bovine leukaemia virus for the cattle with subcutaneous lesions, which would be a potential indicator of the infection of bovine leukaemia, should be prioritised.