Browsing by Autor "Laura Pamela Mamani Manzaneda"

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Artificial intelligence, education and digital inclusion
(2025) Jhossmar Cristians Auza-Santiváñez; Nayra Condori-Villca; Isaura Oberson Santander; Luis Mariano Tecuatl Gómez; Laura Pamela Mamani Manzaneda; Adalid Rimer Condo-Gutierrez; Ariel Sosa Remón; Manashree Mane; José Alejandro Carías Díaz; Freddy Ednildon Bautista-Vanegas
Introduction: The rapid development of human scientific endeavor has enabled the implementation of increasingly automated systems that facilitate certain functions and processes in all spheres of life. Objective: To describe the application of artificial intelligence in education as a strategy to ensure digital inclusion. Method: A comprehensive literature review was conducted. The search was conducted in: SCielo, PubMed, and SCOPUS, repositories, and the Google Scholar search engine. The search strategy consisted of descriptors. 32 papers were used to develop this article. Development: AI provides significant tools, from the graphic representation of content in educational contexts to the creation of conceptual maps and the development of tests to validate acquired knowledge. However, its use must be urgent without losing the guiding and methodological thread, always recognizing that the goal is the acquisition of knowledge. Universities require projection at different scales to present their results for the sake of sociocultural and academic scientific development. With the implementation of AI, this outreach function can be fulfilled, guaranteeing direct and personalized access and promoting digital inclusion. Conclusions: The use of AI in educational subjects offers new platforms and work scenarios. Each of its capabilities adapts to the specifics of the educational environment, while also enhancing easy, affordable, and universal access to educational content.
Bibliographic review on the application of biomaterials in neurological disorders
(2025) Jhossmar Cristians Auza-Santiváñez; Freddy Ednildon Bautista-Vanegas; José Alejandro Carías Díaz; Blas Apaza-Huanca; Ariel Sosa Remón; Adalid Rimer Condo-Gutierrez; Laura Pamela Mamani Manzaneda; Luis Mariano Tecuatl Gómez; Isaura Oberson Santander; Nayra Condori-Villca
Introduction: the process of endogenous neurogenesis is not capable of replenishing lost cells after an injury that can result in massive cell loss. Biomaterials are being developed to mimic the brain’s extracellular matrix, providing scaffolds that promote tissue repair and regeneration. The objective was to characterize the application of biomaterials in neurological affections.Methods: a literature review was conducted, where 20 articles in English and Spanish were selected, published in the last five years on the subject, in databases such as: Scopus, PubMed, Springer.Results: biomaterials play an essential role in the human body by serving as artificial substitutes or implants that interact with living tissues, organs, and bodily fluids. Emerging approaches, including stem cell therapy, biomaterials, immune cell therapy, and exosome-based treatments, show promise in modulating the inflammatory response while avoiding broad suppression of immune function. With that in mind, researchers are exploring how these materials could help repair nerve damage once thought to be permanent, boost brain function, and play a key role in fields like neuro-oncology and neuro-rehabilitation. Conclusions: biomaterials enable safe contact with living tissue and offer promise in neuroscience. Research is still needed to address ethics and ensure safe use.
Difficult Airway in Adult patients: Outcome and institutional response
(2023) Ángel Roberto Martínez López; José Alejandro Carías Díaz; Jhossmar Cristians Auza-Santiváñez; Gustavo Perez-Aramayo; Laura Pamela Mamani Manzaneda; Pablo Saul Mayta-Amador; Blas Apaza-Huanca
Introduction. The airway is one in which a trained anesthesiologist experiences difficulty in ventilation or difficulty in intubation, or both. Objective. To determine the outcome of patients over 18 years of age with a difficult airway and the characteristics of the institutional response capacity, at the Hospital Escuela Universitario, Tegucigalpa, Honduras. 2018-2020. Methods. Descriptive Cross-Sectional Study, with a sample of 80 patients with difficult airway. Non-probability sampling for convenience. The data were entered in EPI-INFO. Descriptive analysis was performed as measures of central tendency and grouping. The proportion was estimated using the formula: P = Number of people with difficult airways / number of patients older than 18 years multiplied by 100. The protocol was approved by the Ethics Committee in Biomedical Research / FCM / UNAH. Results. 28,8 % had ASA II anesthetic risk, 27,6 % had ASA IIE. 68,5 % had Grade III Cormack Lehane Scale, 7,5 % Grade II, 23,7 % Grade IV, 97,5 % of the intubation was successful, 2,5 % was unsuccessful. 36,3 % with a difficult airway are overweight, 25 % are type I obese, 13,8 % are type III obese and 8,3 %. There was 97,2 % of successful intubation and, in most, up to 2 attempts were required to achieve it. Conclusions. Obesity constitutes a risk factor for difficult ventilation and intubation, as well as an anesthetic risk. ASA II and III is also a risk factor for difficult airway.
Factors of interest of general practitioners in scientific research in first-level care centers in Bolivia
(2024) Laura Pamela Mamani Manzaneda; Jhossmar Cristians Auza-Santiváñez; Blas Apaza-Huanca; Nayra Condori-Villca; Boris Adolfo Llanos Torrico; Germán José Martín Rico Ramallo; Zuzel Salazar Duany; Roberto Carlos Jiménez Fernández
Introduction: publication, as part of scientific and academic communication, is a key element of the ethical and moral obligation of every researcher. Our study addresses the factors of interest that general practitioners have in scientific research in first-level public health care centers in the municipality of El Alto. Objective: determine the factors of interest that general practitioners have in scientific research in first-level public health care centers in the municipality of El Alto, department of La Paz, Bolivia. Methods: it is a qualitative, descriptive, analytical and cross-sectional study, under a non-experimental design. The universe consisted of 3,520 general practitioners in the department of La Paz, 103 general practitioners agreed to participate as a sample of the research, and who met inclusion and exclusion criteria. Results and discussion: 68 % of the doctors are between 31 and 40 years old. 46,6 % graduated from a university abroad, however it had no impact on the research process. 62,1 % of all doctors have an academic degree at the bachelor's level. The majority of doctors after graduating do not continue with higher professional training studies. 80,6 % did not publish scientific articles. 41,7 % indicate that they do not carry out scientific research because there is no institutional support. Conclusions: the majority of doctors who participated in our study are relatively young – adults. Regardless of the school they graduate from, it has no impact on the research processes. Their academic degree is a bachelor's degree, followed by diplomas and none with a doctorate. After graduating, they do not continue with higher or postgraduate studies. The vast majority of doctors do not publish any research articles. Based on these results, it is necessary to implement strategies that encourage the development of research in general practitioners at the first level of care
Improvements in functionality and quality of life after aquatic therapy in stroke survivors
(2023) Jhossmar Cristians Auza-Santiváñez; Nayra Condori-Villca; Isaura Oberson Santander; Luis Mariano Tecuatl Gómez; Laura Pamela Mamani Manzaneda; Adalid Rimer Condo-Gutierrez; Ariel Sosa Remón; Blas Apaza-Huanca; José Alejandro Carías Díaz; Amira Guisel Lopez-Quispe
The paper discusses the vital importance of water in living beings and its application in hydrotherapy for the rehabilitation of stroke patients. Water is highlighted as an essential molecule for life, support of metabolic reactions, transport of substances, and important reactant in metabolic processes. Hydrotherapy, significantly developed by Kneipp, uses the mechanical and thermal properties of water for therapeutic purposes, taking advantage of its capacity as a rehabilitative medium in patients with various conditions, including those affected by stroke. The physiology of stroke is described, being a major cause of mortality and disability, and how water exercises can improve the functional capacity and quality of life of these patients. Hydrotherapy is presented as a beneficial therapeutic option, based on the unique properties of water, for the treatment and rehabilitation of stroke patients, highlighting its potential to improve the mobility and quality of life of those affected.
Puerperal eclampsia in the immediate postoperative period of cesarean section: a critical obstetric emergency
(2025) Laura Pamela Mamani Manzaneda; Jose Antonio Uzeda Peredo; Jhossmar Cristians Auza-Santiváñez; A. M. Blanco; Daniel Ramiro Elías Vallejos-Rejas; Camila Tassoula Egüez-Pereira; Carmen Julia Salvatierra-Rocha; Marlon Carbonell González
Eclampsia is a serious and potentially life-threatening complication of hypertensive disorders of pregnancy, characterized by the onset of new-onset seizures (tonic-clonic, focal, or multifocal) in the absence of other identifiable neurological causes. Most cases of eclampsia manifest postpartum, with the first 48 hours being the highest risk period. Recent literature has documented the emergence of atypical forms of eclampsia, in which seizures can occur in the absence of hypertension or proteinuria. The unpredictable nature of these cases makes timely diagnosis and management difficult. A 29-year-old female patient at approximately 40.6 weeks presented to the emergency department with prodromes of labor. An obstetric ultrasound was performed, and given the diagnosis of risk of loss of fetal well-being, an emergency segmental cesarean section was performed. Approximately four hours after the cesarean section, the patient presented two generalized tonic-clonic seizures. Anticonvulsant treatment was administered, a diagnosis of puerperal eclampsia was established, and her transfer to the Intensive Care Unit (ICU) was coordinated. The therapeutic plan in the ICU included an infusion of phenytoin as an anticonvulsant, antihypertensive management with alpha-methyldopa, hemodynamic support, correction of fluid and electrolyte imbalance, and empirical antibiotic therapy due to suspected urinary tract infection. Her subsequent evolution was favorable, remaining afebrile, hemodynamically stable, and without recurrence of seizures. The unusual presentation of puerperal eclampsia in the immediate postoperative period, in the initial absence of the classic diagnostic criteria of hypertension and proteinuria, is significant and of academic value. This case underscores the importance of maintaining a high level of clinical suspicion for eclampsia in the immediate postpartum period, even without prior criteria for preeclampsia. Early recognition and the timely use of magnesium sulfate are essential to reduce maternal morbidity and mortality.
Quality of life in hypertensive individuals attending a health facility in North Lima
(2023) Milusca Jaqueline Velarde-Tejada; David Fidel Vela-Quico; Fernando Ubaldo Enciso-Miranda; Laura Pamela Mamani Manzaneda; Nancy Rosillo Suárez
La calidad de vida es uno de los principales factores que contribuye en el bienestar de salud de la persona ya sea en buen estado de salud o con alguna enfermedad presente, por lo que su objetivo de investigación es determinar la calidad de vida en personas hipertensas que acuden a un establecimiento sanitario de Lima Norte, 2022. Es un estudio cuantitativo, descriptivo y transversal, con una población total de 150 pacientes diagnosticados con hipertensión arterial, que respondieron un cuestionario de aspectos sociodemográficos y el cuestionario calidad de vida en hipertensos. En los resultados podemos observar que, 71,3% (n=107) tienen una calidad de vida buena, 8% (n=12) una calidad de vida regular y 20,7%(n=31) una calidad de vida mala. Se concluye que, se debe promover los conocimientos acerca de como mejorar su calidad de vida a pacientes con HTA, y que factores pueden poner en riesgo su salud si no se controla de una manera adecuada.
Structural and functional disorders in children’s feet, motor development, and preventive approaches in early life
(2025) Jhossmar Cristians Auza-Santiváñez; Freddy Ednildon Bautista-Vanegas; José Alejandro Carías Díaz; Blas Apaza-Huanca; Ariel Sosa Remón; Adalid Rimer Condo-Gutierrez; Laura Pamela Mamani Manzaneda; Luis Mariano Tecuatl Gómez; Isaura Oberson Santander; Nayra Condori-Villca
Pediatric podiatry addresses structural and functional disorders of the foot in children (0-18 years), which are crucial for motor and postural development and overall health. Children's feet, which are constantly evolving until the age of 14, have tissue plasticity that favors early corrections but also makes them vulnerable to deformities such as flexible flat feet (physiological in infants, resolves spontaneously in >90% of cases), clubfoot (requires early Ponseti method), and adducted metatarsus (90% spontaneous resolution in flexible cases). . Gait abnormalities (intra/extraversion, idiopathic toe walking) are usually normal transient variants. Early detection is vital: persistent pain, limping, visible deformities, or asymmetrical shoe wear require evaluation. Diagnosis combines physical examination (toe walking test, alignment analysis) and imaging (X-ray, MRI) to differentiate physiological variants from pathologies (e.g., tarsal coalition in rigid flatfoot). Key preventive strategies include the use of appropriate footwear, motor stimulation, and good postural/hygienic habits. Multidisciplinary intervention (podiatrist, orthopedist, physical therapist) should take advantage of the window of childhood plasticity (<7 years), prioritizing conservative approaches (orthotics, exercises) over surgical ones. Annual checkups starting at 3-4 years of age optimize prognoses and prevent complications in adulthood.