Browsing by Autor "Linda Awdishu"

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Digital health and acute kidney injury: consensus report of the 27th Acute Disease Quality Initiative workgroup
(Nature Portfolio, 2023) Kianoush Kashani; Linda Awdishu; Sean M. Bagshaw; Erin F. Barreto; Rolando Claure‐Del Granado; Barbara J. Evans; Lui G. Forni; Erina Ghosh; Stuart L. Goldstein; Sandra L. Kane‐Gill
Acute kidney injury (AKI), which is a common complication of acute illnesses, affects the health of individuals in community, acute care and post-acute care settings. Although the recognition, prevention and management of AKI has advanced over the past decades, its incidence and related morbidity, mortality and health care burden remain overwhelming. The rapid growth of digital technologies has provided a new platform to improve patient care, and reports show demonstrable benefits in care processes and, in some instances, in patient outcomes. However, despite great progress, the potential benefits of using digital technology to manage AKI has not yet been fully explored or implemented in clinical practice. Digital health studies in AKI have shown variable evidence of benefits, and the digital divide means that access to digital technologies is not equitable. Upstream research and development costs, limited stakeholder participation and acceptance, and poor scalability of digital health solutions have hindered their widespread implementation and use. Here, we provide recommendations from the Acute Disease Quality Initiative consensus meeting, which involved experts in adult and paediatric nephrology, critical care, pharmacy and data science, at which the use of digital health for risk prediction, prevention, identification and management of AKI and its consequences was discussed.
The role of sex and gender in acute kidney injury—consensus statements from the 33rd Acute Disease Quality Initiative
(Elsevier BV, 2025) Danielle E. Soranno; Linda Awdishu; Sean M. Bagshaw; David P. Basile; Samira Bell; Azra Bihorac; Joseph V. Bonventre; Alessandra Brendolan; Rolando Claure‐Del Granado; David Collister
Sex differences exist in acute kidney injury (AKI), and the role that sex and gender play along the AKI care continuum remains unclear. The 33rd Acute Disease Quality Initiative meeting evaluated available data on the role of sex and gender in AKI and identified knowledge gaps. Data from experimental models, pathophysiology, epidemiology, clinical care, gender, social determinants of health, education, and advocacy were reviewed. Recommendations include incorporating sex and gender into research along the bench-to-bedside spectrum; analyzing sex-stratified results; evaluating the effects of sex chromosomes, hormones, and gender on outcomes; considering fluctuations of hormone levels; studying the impact gender may have on access to care; and developing educational tools to inform patients, providers, and stakeholders. This meeting report summarizes what is known about sex and gender along the AKI care continuum and proposes an agenda for translational discovery to elucidate the role of sex and gender in AKI across the lifespan.