Browsing by Autor "Lourdes Zalles"

Now showing 1 - 4 of 4

["CLAPSEN", a global approach to the rehabilitation of severe childhood malnutrition in Bolivia].
(National Institutes of Health, 2000) Ricardo Sevilla; Edgar Sejas; Lourdes Zalles; Guadalupe Belmonte; Philippe Chevalier; Geneviève J. Parent; Hilderbrand Katherine; Patrick Kolsteren
The "CLAPSEN" approach was developed at the Hospital Materno Infantil German Urquidi in Cochabamba, to provide a global response for the study and treatment of childhood malnutrition. "CLAPSEN" is short for Clinical, Laboratory, Anthropometry, Psychology, Sociology, Nursing (Enfermera in Spanish) and Nutritional care. Most of the malnourished children admitted to Cochabamba Hospital are from poor families, more than three quarters of whom have only recently arrived in the city. Acute malnutrition is just one of the manifestations of a generally unfavorable environment. Malnutrition should not be considered as a simple deficiency in energy, protein or micronutrients, but rather as a multi-deficiency syndrome, also involving a lack of basic health and social care. This study demonstrates that malnourished children display a considerable degree of psychological retardation and of immune system depression. After five weeks of rehabilitation, the children were considered to have recuperated physically, as assessed by anthropometry, but not psychologically, as assessed by the adapted Dewer Score, or immunologically, as shown by the size of the thymus or the extent of maturation of lymphocytes. This strategy was not designed as a long-term approach for treating malnutrition, but rather as a research project to characterize the children arriving at the hospital, to determine the reasons for their malnutrition and to identify strategies that could be implemented earlier by health centers of social services, to prevent deterioration in the condition of these children to severe malnutrition requiring hospital admission. We believe that, in this Latin American context, in which the rate of acute malnutrition is low, the hospital should continue to be involved in the treatment of severely malnourished children with associated diseases. The child's stay in hospital should be short and once the child has recovered clinically, he should be sent home. In light of the observed levels of social deprivation, psychosocial and immune deficits, there appears to be a need for continued support for the family, to ensure the full recovery of the child and to prevent relapses.
Effect of zinc supplementation on nutritional immune deficiency
(Elsevier BV, 1996) Philippe Chevalier; Ricardo Sevilla; Lourdes Zalles; Edgar Sejas; Guadalupe Belmonte
Evaluación del daño renal por cadmio en población expuesta a contaminación por éste en agricultores de Quila-Quila, Potosí
(2020) Carlos Erostegui Revilla; Carla Oporto; Lourdes Zalles; Ricardo Sevilla; Ana Romero
Introduccion: El cadmio es un metal pesado presente en desechos mineros y otros, y tiene efectos deletéreos en la salud humana especialmente en el riñón en el que destruye células tubulares. En una investigación de la calidad del lecho de los ríos que reciben aguas residuales en el norte de Potosí, Bolivia, se reportó presencia de cadmio en papas regadas con esas agua en Quila-quila, una población rural de la zona.El objetivo de ese trabajo fue el de identificar posibles daños del cadmio en la salud de los pobladores de Quila-quila. Metodos: Para ello se realizó revisión clínica y análisis laboratorial clínico y químico de sangre y orina de los pobladores de Quila-quila, y se calculó la tasa de filtración glomerular (TFG) y se correlacionó ésta con indicadores de lesión glomerular. Resultados: Se encontraron niveles elevados de cadmio en sangre en algunas personas, y una correlación de la TFG con la concentración de cadmio en sangre y con indicadores de lesión de membrana glomerular. Conclusiones: En conclusión, los pobladores de Quila-quila estuvieron contaminados por cadmio, el cual produjo lesión renal leve.
In vitro lymphocyte-differentiating effects of thymulin (Zn-FTS) on lymphocyte subpopulations of severely malnourished children
(Elsevier BV, 1994) Geneviève J. Parent; Philippe Chevalier; Lourdes Zalles; Ricardo Sevilla; Matilde Bustos; JM Dhenin; Bernard Jambón