Browsing by Autor "Luis Beingolea"

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CAMBIO CLIMÁTICO Y SALUD EN LA REGIÓN ANDINA
(2009) O. De Feo; Elisa Solano; Luis Beingolea; Marilyn Aparicio; Mario Villagra; M.J. Prieto; J. Ramirez Garcia; P. Citlally Jimenez; Óscar Betancourt; Marcelo Aguilar
"Se presentan de manera resumida las causas fundamentales que contribuyen al calentamiento global y una serie de evidencias de la realidad que nos afecta: aumenta la temperatura de la tierra, se derriten los glaciares, sube el nivel delos océanos y se incrementa la frecuencia e intensidad de los eventos meteorológicos; todo ello como producto de la acumulación inusitada de gases de efecto invernadero, provenientes de la actividad humana. Se plantea las implicaciones que, de forma directa o indirecta, el cambio climático tiene para la salud, en particular para los países andinos: trastornos vinculados con la disponibilidad y calidad del agua y los alimentos, afecciones respiratorias, infecciones de transmisión vectorial, cáncer y enfermedades crónico degenerativas, cuadros asociados con desastres climáticos y temperaturas extremas. Finalmente, se revisa las propuestas y cursos de acción."
Epidemic Cholera in the Amazon: The Role of Produce in Disease Risk and Prevention
(Oxford University Press, 1994) Óscar J. Mújica; Rob Quick; Ana M. Palacios; Luis Beingolea; Rodolfo Vargas; D Moreno; Timothy J. Barrett; Nancy H. Bean; L Seminario; R. V. Tauxe
Epidemic cholera struck Peru in January 1991 and spread within a month to the Amazon headwaters. A case-control study was done in the Amazonian city of Iquitos, Peru. Cholera-like illness was associated with eating unwashed fruits and vegetables (odds ratio [OR] = 8.0; 95% confidence limits [CL] = 2.2, 28.9) and drinking untreated water (OR = 2.9; 95% CL = 1.3, 6.4). Consumption of a drink made from toronja, a citrus fruit, was protective against illness (OR = 0.4; 95% CL = 0.2, 0.7). Illness was inversely associated with the quantity of toronja drink consumed (P < .01). Produce has not previously been convincingly documented as a risk factor for cholera; this study underscores the importance of washing produce before eating it. Acidic juices, such as toronja drink (pH 4.1), inhibit vibrio growth and may make contaminated water safer. Wild citrus fruits such as toronja are abundant, cheap, and popular in the Amazon region. Promoting the consumption of toronja drink may be a useful cholera prevention strategy in this region.
Genetic Characterization of Venezuelan Equine Encephalitis Virus from Bolivia, Ecuador and Peru: Identification of a New Subtype ID Lineage
(Public Library of Science, 2009) Patricia V. Aguilar; Alexandra Adams; Víctor Suárez; Luis Beingolea; Jorge Vargas; Stephen R. Manock; Juan Freire; Willan R. Espinoza; Vidal Felices; Ana María Díaz
Venezuelan equine encephalitis virus (VEEV) has been responsible for hundreds of thousands of human and equine cases of severe disease in the Americas. A passive surveillance study was conducted in Peru, Bolivia and Ecuador to determine the arboviral etiology of febrile illness. Patients with suspected viral-associated, acute, undifferentiated febrile illness of <7 days duration were enrolled in the study and blood samples were obtained from each patient and assayed by virus isolation. Demographic and clinical information from each patient was also obtained at the time of voluntary enrollment. In 2005-2007, cases of Venezuelan equine encephalitis (VEE) were diagnosed for the first time in residents of Bolivia; the patients did not report traveling, suggesting endemic circulation of VEEV in Bolivia. In 2001 and 2003, VEE cases were also identified in Ecuador. Since 1993, VEEV has been continuously isolated from patients in Loreto, Peru, and more recently (2005), in Madre de Dios, Peru. We performed phylogenetic analyses with VEEV from Bolivia, Ecuador and Peru and compared their relationships to strains from other parts of South America. We found that VEEV subtype ID Panama/Peru genotype is the predominant one circulating in Peru. We also demonstrated that VEEV subtype ID strains circulating in Ecuador belong to the Colombia/Venezuela genotype and VEEV from Madre de Dios, Peru and Cochabamba, Bolivia belong to a new ID genotype. In summary, we identified a new major lineage of enzootic VEEV subtype ID, information that could aid in the understanding of the emergence and evolution of VEEV in South America.
Guaroa Virus Infection among Humans in Bolivia and Peru
(American Society of Tropical Medicine and Hygiene, 2010) Patricia V. Aguilar; Amy C. Morrison; Claudio Rocha; Douglas M. Watts; Luis Beingolea; Víctor Suárez; Jorge Vargas; Cristhopher D. Cruz; Carolina Guevara; Joel M. Montgomery
Guaroa virus (GROV) was first isolated from humans in Colombia in 1959. Subsequent isolates of the virus have been recovered from febrile patients and mosquitoes in Brazil, Colombia, and Panama; however, association of the virus with human disease has been unclear. As part of a study on the etiology of febrile illnesses in Peru and Bolivia, 14 GROV strains were isolated from patients with febrile illnesses, and 3 additional cases were confirmed by IgM seroconversion. The prevalence rate of GROV antibodies among Iquitos residents was 13%; the highest rates were among persons with occupations such as woodcutters, fisherman, and oil-field workers. Genetic characterization of representative GROV isolates indicated that strains from Peru and Bolivia form a monophyletic group that can be distinguished from strains isolated earlier in Brazil and Colombia. This study confirms GROV as a cause of febrile illness in tropical regions of Central and South America.