Browsing by Autor "Luisa Valentina Hurtado"

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    HLA-DRB1*1602 allele is positively associated with HPV cervical infection in Bolivian Andean women
    (Elsevier BV, 2003) Jorge Cervantes; Carolina Lema; Luisa Valentina Hurtado; Ronald Andrade; Luis Hurtado Gómez; Lorena Torrico; Lourdes Zegarra; Gladys Quiroga; David Asturizaga; Alfredo Dulon
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    Prevalence of human papillomavirus infection in rural villages of the Bolivian Amazon
    (University of São Paulo, 2003) Jorge Cervantes; Carolina Lema; Luisa Valentina Hurtado; Ronald Andrade; Gladys Quiroga; Giovanni Garcia; Lorena Torricos; Lourdes Zegarra; Verónica Vera; Wilge Panoso
    Cervical cancer constitutes a major health problem in developing countries like Bolivia. The roles of certain genotypes of human papillomaviruses (HPVs) in the pathogenesis of cervical cancer is well established. The prevalence of HPV infection among sexually active women varies greatly. Information regarding HPV infection in Bolivia is very much scarce, specially in regions like the Amazonian lowland. We studied 135 healthy women living in four rural localities of the Bolivian Amazon. Presence of HPV in DNA extracted from cervical swabs was analyzed using a reverse line hybridization assay. The estimated overall HPV infection prevalence among the studied rural localities was 5.9% (ranging from 0-16.6%). These values were unexpectedly low considering Bolivia has a high incidence of cervical cancer. The fact that Amazonian people seem to be less exposed to HPV, makes it likely that some other risk factors including host lifestyle behaviors and genetic background may be involved in the development of cervical cancer in this population.