Browsing by Autor "M Paz-Zamora"

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Effect of altitude on the lung function of high altitude residents of European ancestry
(Wiley, 1988) Lawrence P. Greksa; Hilde Spielvogel; M Paz-Zamora; Esperanza Cáceres; Luis Paredes‐Fernández
The forced vital capacity (FVC), forced expiratory volume in one second (FEV), and ratio of FEV to FVC (%FEV) of 161 male and 158 female youths of European ancestry who were born at high altitudes and who were residing in La Paz, Bolivia (average altitude of 3,600 m) were examined and compared with those for lowland Europeans and highland Aymara Amerindians. FVC and FEV were significantly larger (p less than .001) in the La Paz Europeans than in two lowland control samples of European ancestry, with the relative differences between samples varying from small (1.5-4.1%) to moderate (7.7-11.9%). It could not be determined whether the enhanced lung volumes of the La Paz European children were acquired through an accelerated development of lung volumes relative to stature during adolescence, as is the case for Amerindian highlanders. After controlling for body and chest size, FVC and FEV were significantly smaller in the La Paz Europeans than in highland Aymara (p less than .001), suggesting that the lung volumes of the Aymara are influenced by factors other than simply growth and development at high altitude. Finally, as found in Amerindians, chest size is an important determinant of intra-individual variation in lung function among highland Europeans.
Effects of Hypoxia and Hyperoxia of Short Duration on the Pulmonary Circulation of Highlanders (HL) and Lowlanders (LL) Living at 3,750 m
(2015) J Coudert; M Paz-Zamora; G Antezana; Enrique Vargas; L. Brian�on
Performance of altitude acclimatized and non-acclimatized professional football (soccer) players at 3,600 M
(2000) Tom D. Brutsaert; Hilde Spielvogel; Rudy Soria; Mauricio Araoz; Esperanza Cáceres; Giliane Buzenet; Mercedes Villena; M Paz-Zamora; Enrique Vargas
Regional Distribution of Pulmonary Blood Flow in Normal High-Altitude Dwellers at 3,650 m (12,200 ft)
(Karger Publishers, 1975) J Coudert; M Paz-Zamora; L. Barragán; L Briançon; Hilde Spielvogel; L. Cudkowicz
Simultaneous isotope dilution curves were recorded from the right upper (QRUZ) and right lower lung zones (QRLZ) by surface scanning in the sitting and recumbent positions in 15 normal high-altitude-born (HAD) males and in 1 HAD female as well as from 3 male newcomers, using 10 muCi of 131I-HSA as a bolus injection into the right ventricle. Similar information was also obtained at sea level from 5 normal males. The mean percent distribution of total pulmonary blood flow (Q) to RUZ and RLZ in the two body postures indicate (1) that in the vertical position RUZ in males receives about 17% of Q regardless of altitude and elevation in mean pulmonary artery pressure (MPAP) in HAD of 8.6 mm Hg above that extant at sea level; (2) recumbency at high altitude showed QRUZ also to be lower than at sea level; (3) elevation in MPAP at altitude has no significant effect on changing the sea-level distribution pattern of pulmonary blood flow.
The physical growth of urban children at high altitude
(Wiley, 1984) Lawrence P. Greksa; Hilde Spielvogel; Luis Paredes‐Fernández; M Paz-Zamora; Esperanza Cáceres
The physical growth of urban Aymara children residing in La Paz, Bolivia (3,600 m) is described and compared with Amerindian children residing at low and high altitudes and with low-altitude U.S. children. The sample consists of 227 males (10.6-19.7 yr) and 219 females (11.2-19.8 yr). The urban La Paz children were taller at all ages than rural high altitude Amerindian children but similar in stature to urban high altitude children from Peru. The variation in stature among the high altitude populations was considerable, amounting to average differences between the tallest and shortest samples of about 10 cm in males and 8 cm in females. In addition, stature in the two urban high altitude samples was similar to that of rural low-altitude Amerindians. This overlapping of the distributions of stature in high- and low-altitude populations could easily confound comparisons designed to determine the effects of hypoxia on physical growth. La Paz Aymara children had considerably smaller chest sizes relative to stature than high-altitude Quechua children. However, the available data indicates that relative chest sizes are similar in Aymara and Quechua adults, suggesting that the process by which large chests are achieved may differ between these Andean populations.
The regional distribution of pulmonary blood flow in normal high altitude dwellers at 3650 m (12,200 ft) and in chronic mountain sickness
(Elsevier BV, 1977) L. Cudkowicz; J Coudert; M Paz-Zamora; L. Barragán; L Briançon; Hilde Spielvogel; Nicanor Machicao; Magda Karina López Saldaña