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Browsing by Autor "M. Recacoechea"

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    A simple method for the collection of material from cutaneous and mucocutaneous leishmaniasis lesions
    (Oxford University Press, 1983) R. Urjel; M. Recacoechea; C. La Fuente; H Orellana
    Journal Article A simple method for the collection of material from cutaneous and mucocutaneous leishmaniasis lesions Get access R Urjel, R Urjel Centro Nacional de Enfermedades Tropicales (CENETROP), Casilla 2974, Santa Cruz, Bolivia Search for other works by this author on: Oxford Academic PubMed Google Scholar M Recacoechea, M Recacoechea Centro Nacional de Enfermedades Tropicales (CENETROP), Casilla 2974, Santa Cruz, Bolivia Search for other works by this author on: Oxford Academic PubMed Google Scholar C La Fuente, C La Fuente Centro Nacional de Enfermedades Tropicales (CENETROP), Casilla 2974, Santa Cruz, Bolivia Search for other works by this author on: Oxford Academic PubMed Google Scholar H Orellana H Orellana Centro Nacional de Enfermedades Tropicales (CENETROP), Casilla 2974, Santa Cruz, Bolivia Search for other works by this author on: Oxford Academic PubMed Google Scholar Transactions of The Royal Society of Tropical Medicine and Hygiene, Volume 77, Issue 6, 1983, Pages 882–883, https://doi.org/10.1016/0035-9203(83)90325-5 Published: 01 January 1983 Article history Published: 01 January 1983 Accepted: 03 August 1983
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    Ketoconazole in the Treatment of Paracoccidioidomycosis (South American Blastomycosis). Experience in 30 Cases in Bolivia/Ketoconazol in der Behandlung der Paracoccidioidomykose (Südamerikanische Blastomykose). Auswertung von 30 Fällen in Bolivien
    (Wiley, 1988) Jorge Vargas; M. Recacoechea
    Summary: The results for 30 patients suffering from paracoccidioidomycosis and treated orally with ketoconazole are reported. The patients (28 men and 2 women aged 5–70) presented a variety of pure and/or mixed clinical forms of this systemic mycosis. The process was primary in 25 cases and recurrent in 5. Nine patients had previously been treated with amphotericin B, miconazole, and sulphonamides. Ketoconazole was administered in doses of 200 mg/12 h (400 mg/day) for periods of 3 to 7 months. According to the established criteria, the results were classified as “very good” (clinical and laboratory cure) in 25 patients (83%) and as “good” (clinical improvement, variable laboratory response) in 3 patients (10%). No cases of a “poor” response to the treatment were recorded and 2 cases could not be assessed owing to a lack of examination data. No relapses were observed in the after‐treatment check‐ups carried out in 20 patients (up to 12 months after discontinuation of treatment). Adverse reactions and toxic effects were minimal. The overall results show that ketoconazole is the preferred choice of drug for the treatment of paracoccidioidomycosis. Zusammenfassung: Die Ergebnisse von 30 Patienten mit Paracoccidioidomykose nach oraler Behandlung mit Ketoconazol werden vorgelegt. Die Patienten (28 Männer, 2 Frauen, Altersgrenzen 5–70 Jahre) zeigten eine Vielzahl reiner und/oder gemischter klinischer Formen dieser Systemmykose. Die Erkrankung war bei 25 Patienten erstmalig, bei 5 rezidivierend. Neun Patienten waren vorher mit Amphoterizin B, Miconazol bzw. Sulfonamiden behandelt worden. Ketoconazol wurde in Dosen von 200 mg/12 h (400 mg/d) über Zeiträume von 3 bis 7 Monaten verabreicht Die Ergebnisse wurden nach festgesetzten Kriterien bei 25 Patienten (83%) als “sehr gut” (klinische Heilung mit mykologischer Sanierung) und bei 3 Patienten (10%) als “gut” (klinische Besserung, unterschiedliche Laborergebnisse) beurteilt. Kein Patient zeigte ein “schlechtes” Behandlungsergebnis, aber das Fehlen von Untersuchungsdaten bei 2 Patienten schloß deren Beurteilung aus. In den bis 12 Monate nach Behandlungsende durchgeführten Nachuntersuchungen an 20 Patienten wurden keine Rezidive beobachtet. Das Auftreten von toxischen und Nebenwirkungen war minimal. Aus den Gesamtergebnissen geht hervor, daß Ketoconazol bei der Behandlung der Paracoccidioidomykose das Arzneimittel der Wahl ist.
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    Leishmaniasis in the Lowlands of Bolivia (Leishbol): Part II. Community Health Care for Spontaneous Settlers in Endemictropical Forest
    (1989) G Villarroel; M. Recacoechea; S. Balderrama
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    Leishmaniasis in the Lowlands of Bolivia (Leishbol): Part III. Status of the Disease in an Area of Spontaneous Agricultural Colonization
    (1989) M. Recacoechea; G Villarroel; S. Balderrama; R. Urjel; Simonne De Doncker; D. Jacquet; D. Le Ray
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    Leishmaniasis in the Lowlands of Bolivia (Leishbol): Part VII. Preliminary Characterization of Eleven Leishmania Isolates
    (1989) R. Urjel; M. Recacoechea; P. Desjeux; Harry Bermudez; G Villarroel; S. Balderrama; José Miguel Carrasco; Olga Aguilar; J. Cl. Dujardin; D. Le Ray
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    Leishmaniasis in the Lowlawnds of Bolivia (Leishbol): Part VIII. Characterization and Identification of Bolivian Isolates by PFG Karyotyping
    (1989) J. Cl. Dujardin; Nadesan Gajendran; R. Hamers; G. Matthijsen; R. Urjel; M. Recacoechea; G Villarroel; Harry Bermudez; P. Desjeux; Simonne De Doncker

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