Browsing by Autor "Manuel Segovia"
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Item type: Item , Impact of benznidazole treatment on the functional response of Trypanosoma cruzi antigen-specific CD4+CD8+ T cells in chronic Chagas disease patients(Public Library of Science, 2018) Elena Pérez-Antón; Adriana Egui; M. Carmen Thomas; Concepción J. Puerta; John Mario González; Adriana Cuéllar; Manuel Segovia; Manuel Carlos LópezCD4+CD8+ T cells could play an important role in the control of T. cruzi infection since they were able to produce effector molecules for parasite control. Benznidazole treatment partially reversed the exhaustion process caused by T. cruzi infection in these cells with an improvement in the functional response of the T. cruzi antigen-specific CD4+CD8+ T cells.