Browsing by Autor "Natalia Valenzuela"

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    Molecular epidemiology of carbapenem-resistant Acinetobacter baumannii in South America
    (Microbiology Society, 2016) Carlos Hernán Rodríguez; Norah Balderrama Yarhui; Marcela Nastro; Tamara Nuñez Quezada; Glenda Castro Cañarte; Raquel Magne Ventura; Tayita Ugarte Cuba; Natalia Valenzuela; Freddy Roach; María Inés Mota
    One hundred and twenty-six epidemiologically sequential, unrelated, carbapenem-resistant Acinetobacter baumannii isolates from nine hospitals in six countries of South America were collected between July 2013 and June 2014. Genes coding for Ambler class D and B carbapenemases were sought by PCR. All isolates were typed using the 3-locus sequence typing and blaOXA-51-like sequence-based typing techniques. The blaOXA-23 gene was recovered in all the participating hospitals and in all the isolates of seven of nine medical centres. The blaOXA-72 gene was only recovered in the two medical centres from Guayaquil city, Ecuador. Trilocus sequence typing revealed the presence of sequence groups SG2, SG4 and SG5. blaOXA-51-like sequence-based typing revealed the presence of blaOXA-132, blaOXA-65, blaOXA-69 and blaOXA-64. Our results showed that the population of carbapenem-resistant A. baumannii in South America was principally associated with ST79, ST25 and ST15 (92 %) and harboured the blaOXA-23 gene mainly. CC2 was not detected.