Browsing by Autor "Ramiro Cabrera"

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    PP007 [Infections » Covid-19 / Sars-CoV-2]: A NOBEL SCORE TO PREDICT PEDIATRIC COVID-19 SEVERITY IN LOW AND MIDDLE INCOME COUNTRIES
    (Lippincott Williams & Wilkins, 2022) Cristian Roca; Raúl Copana Olmos; A. Asturizaga; N. Villca; Ramiro Cabrera; V. Aguilera Avendaño; C. Estrada Villarroel; M. Forest Yepez; M. Torrez Santos; A. Magne Calle
    Roca, C.; Copana Olmos, R.; Asturizaga, A.; Villca, N.; Cabrera, R.; Aguilera Avendaño, V.; Estrada Villarroel, C.; Forest Yepez, M.; Torrez Santos, M.; Magne Calle, A.; Foronda Rios, M.; Torrez, D.; Toco, M.; Cespedes, M.; Davalos, I.; Bowman, N. Author Information
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    Relationship between sociodemographic, clinical, and laboratory characteristics and severity of COVID-19 in pediatric patients
    (Public Library of Science, 2024) Cristian Roca; Adriana Asturizaga; Nelson Villca; Ramiro Cabrera; Raúl Copana-Olmos; Vladimir Aguilera-Avendaño; Claudia Estrada-Villarroel; Mariel Andrea Forest-Yepez; Marcia Torrez-Santos; Adela Felipa Magne-Calle
    COVID-19 affects children less seriously than adults; however, severe cases and deaths are documented. This study objective is to determine socio-demographic, clinical and laboratory indicators associated with severe pediatric COVID-19 and mortality at hospital entrance. A multicenter, retrospective, cross-sectional study was performed in 13 tertiary hospitals in Bolivia. Clinical records were collected retrospectively from patients less than 18 years of age and positive for SARS-CoV-2 infection. All variables were measured at hospital entrance; outcomes of interest were ICU admission and death. A score for disease severity was developed using a logistic regression model. 209 patients were included in the analysis. By the end of the study, 43 (20.6%) of children were admitted to the Intensive care unit (ICU), and 17 (8.1%) died. Five indicators were independently predictive of COVID-19 severity: age below 10 years OR: 3.3 (CI95%: 1.1–10.4), days with symptoms to medical care OR: 2.8 (CI95%: 1.2–6.5), breathing difficulty OR: 3.4 (CI95%: 1.4–8.2), vomiting OR: 3.3 (CI95%: 1.4–7.4), cutaneous lesions OR: 5.6 (CI95%: 1.9–16.6). Presence of three or more of these risk factors at hospital entrance predicted severe disease in COVID-19 positive children. Age, presence of underlying illness, male sex, breathing difficulty, and dehydration were predictive of death in COVID-19 children. Our study identifies several predictors of severe pediatric COVID-19 and death. Incorporating these predictors, we developed a tool that clinicians can use to identify children at high risk of severe COVID-19 in limited-resource settings.