Browsing by Autor "Roberto P. Stock"

Now showing 1 - 5 of 5

Characterization of a new polyvalent antivenom (Antivipmyn® Africa) against African vipers and elapids
(Elsevier BV, 2008) Blanca Ramos‐Cerrillo; Adolfo Rafael de Roodt; Jean‐Philippe Chippaux; Laura Olguín; Andrea Casasola; Guadalupe Guzmán; Jorge Paniagua-Solís; Alejandro Alagón; Roberto P. Stock
Clinical Trial of an F(ab’)2 Polyvalent Equine Antivenom for African Snake Bites in Benin
(American Society of Tropical Medicine and Hygiene, 2007) Jean‐Philippe Chippaux; Achille Massougbodji; Roberto P. Stock; Alejandro Alagón; _ _
We report the results of a trial designed to measure the safety and efficacy of African Antivipmyn, a new freeze-dried polyvalent equine F(ab')(2)-based antivenom. We tested 289 envenomations. After treatment, 19% of treated patients had undesirable events, all benign. A possible adverse effect was attributed to this antivenom in 11% of the patients. Bleeding was observed in 48% of the patients; it stopped within 2 hours after treatment with antivenom in 60% of the patients. Blood incoagulability was observed in 80% of the patients. Restoration of coagulation was attained within 4 hours in 60% of the patients. Nine patients died; 6 arrived at the hospital in the final stage of complications and 5 arrived at the hospital more than 60 hours after the bite. The value of blood coagulation tests in diagnosis of envenomation and bleeding as an indicator of renewal of treatment are emphasized.
Paraspecific neutralization of the venom of African species of cobra by an equine antiserum against Naja melanoleuca: A comparative study
(Elsevier BV, 2009) Andrea Casasola; Blanca Ramos‐Cerrillo; Adolfo Rafael de Roodt; Alejandro Carbajal Saucedo; Jean‐Philippe Chippaux; Alejandro Alagón; Roberto P. Stock
[Report of the 3rd International Conference on Envenomations in Africa].
(National Institutes of Health, 2008) Jean‐Philippe Chippaux; A Massougbodji; Roberto P. Stock; J Akiana; E Mokondjimobé; Parra Hj
The 3rd International Conference on Envenomations was held in Brazzaville from 15 to 17 November; 2007. At this meeting, updating of epidemiological and treatment information on envenomations in Africa were presented. A round table concluded the conference drawing contributors' main recommendations. One of these recommendation pointed out the need to treat the problem of envenimations at a regional level by creating a group of experts in charge of considering the priorities as well as identifying relevant strategies of management, ensuring the plea and finding the financing.
Study of the efficacy of the black stone on envenomation by snake bite in the murine model
(Elsevier BV, 2006) Jean‐Philippe Chippaux; Blanca Ramos‐Cerrillo; Roberto P. Stock