Browsing by Autor "Ronald Palacios Castrillo"

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    Long Covid and Serious Side Reactions to mRNA-Based Vaccines (VSITV) Are Mainly Spike Protein-Induced Thrombotic Vasculitis
    (2023) Ronald Palacios Castrillo
    Long COVID syndrome, known as Long COVID, refers to a series of debilitating symptoms that arise after infection with the SARS-CoV-2 virus. These symptoms are similar to those experienced by some people after vaccination with vaccines based on mRNA platforms (Pfizer, Moderna). With more than 200 million Long COVID patients worldwide and an increase in cases of moderate to severe reactions after administration of mRNA vaccines (VSITV), the effects on quality of life and economics are significant, for what is necessary to pay urgent attention to understand its pathophysiology and to provide an adequate diagnosis and treatment. In this article, we describe our perspective that both Long COVID and common side effects of mRNA vaccines (VSITV) induce persistent and prolonged expression of the spike protein (SPIKE) in various tissues and organs of the body. This would induce coagulopathy, microscopic vasculitis, and endothelitis as the main drivers of the disease, and may also cause or worsen other common pathologies in Long COVID, such as mast cell activation syndrome, dysautonomia, and sudden deaths due to arrhythmias and heart attacks, reports of which continue to rise. Given that the SARS-CoV-2 spike protein can independently induce fibrinoid microclot formation, platelet activation, and endothelitis, we predict that the persistence of the spike protein will be a key mechanism driving ongoing coagulopathy in Long COVID and in the VSITV. We discuss various treatment goals to address coagulopathy, endothelitis, and vasculitis and predict that treatment, especially if given early, with a combination of anticoagulants, antiplatelets, corticosteroids, and rapamycin/everolimus, will provide significant relief for many patients. To focus attention on these treatment targets, we propose that the term Long COVID be changed to "natural Spike Protein-Induced Thrombotic Vasculitis" (NSITV) and that serious side effects of mRNA vaccines be renamed "Vaccine Spike Protein - Induced Thrombotic Vasculitis" (VSITV). Are mainly due to a persistent and disseminated cellular expression of the Spike protein". These ideas require urgent testing, especially as the world tries to live with COVID-19.
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    Unraveling the tapestry: Immune imprinting amidst a spectrum of challenges for modRNA Covid-19 vaccines
    (2024) Ronald Palacios Castrillo
    Immunological imprinting is another road block added to the many obstacles and side effects, including some very serious including deaths), concerning the effectiveness and safety of the modRNA based Covid-19 vaccines.Together, they make it highly unethical and difficult to support/promote the widespread vaccination of children and adults with these vaccines.