Browsing by Autor "Roxana Challapa Quechover"

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    Five-year serological and clinical evolution of chronic Chagas disease patients in Cochabamba, Bolivia
    (Public Library of Science, 2023) Jimy Pinto; Malia Skjefte; Julio Alonso-Padilla; Daniel Franz Lozano Beltrán; Lilian Pinto; Aina Casellas; Mery Elena Arteaga Terrazas; Karen Galindo; Roxana Challapa Quechover; María Escobar Caballero
    The study confirms that follow-up of benznidazole-treated T. cruzi-infected patients should be longer than five years to determine, with current tools, if they are cured. In terms of serological evolution, the single use of a total antigen ELISA might be a more reliable measure and suffice to address infection status, at least in the region of Bolivia where the study was done. Additional work is needed to develop a test-of-cure for an early assessment of drugs´ efficacy with the aim of improving case management protocols.