Browsing by Autor "Silvia Medina-Medina"

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Bacillary Layer Detachment in an Atypical Case of Central Serous Chorioretinopathy Associated with High Hyperopia
(Karger Publishers, 2022) Sergio A. Murillo; Silvia Medina-Medina; Rosa Maria Romero; Fernando H. Murillo
A 16-year-old boy with elevated hyperopia presented to the office with a 24-h history of bilateral blurred vision, mainly of the left eye, and bilateral central serous chorioretinopathy. He showed a clinically recognizable bacillary layer detachment in one eye and excellent multimodal diagnostic image correlation, with the best-corrected visual acuity as 20/400. He had bilateral serous retinal detachment, as confirmed by optical coherence tomography. Laser photocoagulation was performed with good results, and reestablishment of the foveal anatomical structure was documented 16 days after treatment.
Bilaminar Graft of the Anterior Capsule and Internal Limiting Membrane: A Novel Surgical Technique for the Treatment of Macular Hole and Focal Macular Detachment Associated with High Myopia and Posterior Staphyloma
(Karger Publishers, 2022) Sergio A. Murillo; Rosa Maria Romero; Silvia Medina-Medina
This case report describes a novel surgical technique for the treatment of macular hole and focal macular detachment associated with high myopia and posterior staphyloma. A 65-year-old female presented with a stage 3C myopic traction maculopathy and VA of 20/600. OCT examination confirmed a macular hole of 958 μm diameter, posterior staphyloma, and macular detachment. We performed combined phacoemulsification surgery with 23G pars plana vitrectomy; the anterior capsule was preserved and divided into two equal circular laminar flaps. We proceeded with central and peripheral vitrectomy, brilliant blue staining, and partial ILM peeling; capsular sheets were introduced sequentially in the vitreous chamber, the first one was implanted below the hole and attached to pigment epithelium, the second lamina was inserted into the hole, and the remaining portion of ILM was implanted crosswise below the edges of the hole. Macular-hole closure and progressive reapplication of the macular detachment were obtained, with a final VA of 20/80. Treatment of macular holes and focal macular detachment in high myopic eyes is complex, even for experienced surgeons. We propose a new technique with additional mechanisms based on anterior lens capsule and internal limiting membrane tissue properties that showed functional and anatomical improvement and could be considered an alternative treatment.
OCT Features of the Donor Area in Autologous Retinal Transplant Surgery for Macular Hole
(SAGE Publishing, 2024) Silvia Medina-Medina; Abel Ramírez-Estudillo; Sergio Rojas Juárez
Purpose: To describe the structural features of the autologous retinal transplant donor tissue area seen on optical coherence tomography (OCT). Methods: This observational prospective study included patients who had vitrectomy and autologous retinal graft surgery for a macular hole. OCT of the donor area was performed in the postoperative period after gas reabsorption (mean, 16.2 days ±9.8 [SD] after surgery; range, 7 to 28 days), and structural findings in the harvest area were recorded and analyzed. Results: Of the 12 eyes included in the series, most showed glial tissue or some migration of the inner nuclear layer (INL) in the donor area. Hyperreflective dots and epiretinal membranes were present in a few cases; 2 eyes showed denuded retinal epithelial pigment. Conclusions: OCT revealed changes in the donor area, predominantly filled with glial tissue, INL migration, and inflammatory signs, that mostly resolved during follow-up.
Retinal vasculitis associated with intravitreal bevacizumab injection: A case report
(Elsevier BV, 2025) S. Murillo-Lopez; Silvia Medina-Medina
Anti-vascular endothelial growth factor drugs are the treatment of choice for macular edema due to venous occlusions. While rare, they have been associated with some uncommon adverse effects. We present a case of retinal vasculitis associated with bevacizumab in a72-year-old woman who presented to our clinic with sudden visual acuity loss in her left eye due to macular edema following central vein occlusion. She was treated with bevacizumab, with a minor inflammatory response that resolved with topical steroids. After 6 weeks, the macular edema recurred and a 2nd dose of bevacizumab was indicated, with a severe inflammatory reaction that resolved with periocular steroids and topical NSAIDs. Systemic vasculitis and infectious diseases were ruled out and treatment was switched to aflibercept with no adverse effects being reported.
Vasculitis retiniana asociada a inyección intravítrea de bevacizumab: reporte de caso
(Elsevier BV, 2025) S. Murillo-Lopez; Silvia Medina-Medina
Los fármacos anti-factor de crecimiento vascular endotelial son el tratamiento de elección para el edema macular secundario a oclusión venosa; aunque sus efectos secundarios han sido previamente descritos, estos suelen ser raros. A continuación, presentamos un caso de vasculitis retiniana asociada a bevacizumab en una paciente de 72 años que acudió a consulta por edema macular secundario a oclusión de vena central de la retina, por lo que fue tratada con bevacizumab intravítreo. Posteriormente presentó una respuesta inflamatoria mínima que fue resuelta con esteroides tópicos. Seis semanas después se detectó recurrencia del edema macular por lo que se aplicó una segunda dosis de bevacizumab, en esta ocasión con una respuesta inflamatoria severa que requirió tratamiento con esteroides paraoculares y antiinflamatorios no esteroideos tópicos. Se descartó la presencia de vasculitis sistémica y enfermedades infecciosas y se decidió cambiar el tratamiento intravítreo a aflibercept, con el que no se presentaron efectos adversos. Anti-vascular endothelial growth factor drugs are the treatment of choice for macular edema due to venous occlusions. While rare, they have been associated with some uncommon adverse effects. We present a case of retinal vasculitis associated with bevacizumab in a72-year-old woman who presented to our clinic with sudden visual acuity loss in her left eye due to macular edema following central vein occlusion. She was treated with bevacizumab, with a minor inflammatory response that resolved with topical steroids. After 6 weeks, the macular edema recurred and a 2 nd dose of bevacizumab was indicated, with a severe inflammatory reaction that resolved with periocular steroids and topical NSAIDs. Systemic vasculitis and infectious diseases were ruled out and treatment was switched to aflibercept with no adverse effects being reported.