Browsing by Autor "Tayita Ugarte Cuba"

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    Detección serológica directa de hipotiroidismo congénito vs. método del papel filtro
    (2015) Marcos Medina Bustos; Tayita Ugarte Cuba; Ximena Gómez Paz; A Ivonne Condori
    ResumenObjetivos: demostrar la utilidad del metodo serologico directo para deteccion de hipotiroidismo congenito.Metodos: es un estudio transversal, comparativo; destinado a comparar la capacidad diagnostica de la tecnica del papel filtro con la deteccion serologica directa de TSH neonatal en el mismo grupo de neonatos examinados. Se incluyo a 202 Recien Nacidos sanos del Hospital Materno Infantil Cochabamba, entre las 48 hrs. y los 21 dias de vida; en el primer trimestre del ano 2014. El analisis estadistico se realizo comparando las curvas de sensibilidad y especificidad con el Receiver Operating Characteristic (Caracteristica Operativa del Receptor), del paquete estadistico especializado MedCalc, version 12.7. El analisis descriptivo se realizo con el paquete estadistico SPSS-IBM STADISTIC, version 19.Resultados: ambas tecnicas mostraron sensibilidad y especificidad altas, con un area bajo la curva de ambas, cercana a 0.972 (ROC), IC 0,941 - 0,989, al 95%. Conclusiones: ambas tecnicas demostraron ser eficientes en la pesquisa diagnostica de hipotiroidismo congenito. Palabras claves: hipotiroidismo congenito; quimioluminiscencia; inmunofluorometria.
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    Molecular epidemiology of carbapenem-resistant Acinetobacter baumannii in South America
    (Microbiology Society, 2016) Carlos Hernán Rodríguez; Norah Balderrama Yarhui; Marcela Nastro; Tamara Nuñez Quezada; Glenda Castro Cañarte; Raquel Magne Ventura; Tayita Ugarte Cuba; Natalia Valenzuela; Freddy Roach; María Inés Mota
    One hundred and twenty-six epidemiologically sequential, unrelated, carbapenem-resistant Acinetobacter baumannii isolates from nine hospitals in six countries of South America were collected between July 2013 and June 2014. Genes coding for Ambler class D and B carbapenemases were sought by PCR. All isolates were typed using the 3-locus sequence typing and blaOXA-51-like sequence-based typing techniques. The blaOXA-23 gene was recovered in all the participating hospitals and in all the isolates of seven of nine medical centres. The blaOXA-72 gene was only recovered in the two medical centres from Guayaquil city, Ecuador. Trilocus sequence typing revealed the presence of sequence groups SG2, SG4 and SG5. blaOXA-51-like sequence-based typing revealed the presence of blaOXA-132, blaOXA-65, blaOXA-69 and blaOXA-64. Our results showed that the population of carbapenem-resistant A. baumannii in South America was principally associated with ST79, ST25 and ST15 (92 %) and harboured the blaOXA-23 gene mainly. CC2 was not detected.