Browsing by Autor "V. Alberto Laguna-Torres"

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Arboviral Etiologies of Acute Febrile Illnesses in Western South America, 2000–2007
(Public Library of Science, 2010) Brett M. Forshey; Carolina Guevara; V. Alberto Laguna-Torres; Manuel Céspedes; Jorge Vargas; Alberto Gianella; Efraín Vallejo; César Madrid; Nicolás Aguayo; Eduardo Gotuzzo
Our data provide a better understanding of the geographic range of arboviruses in South America and highlight the diversity of pathogens in circulation. These arboviruses are currently significant causes of human illness in endemic regions but also have potential for further expansion. Our data provide a basis for analyzing changes in their ecology and epidemiology.
CARÁCTERÍSTICAS CLÍNICAS Y MOLECULARES DE UN BROTE DE INFLUENZA EN DOS BASES MILITARES, TUMBES- PERÚ, 2007
(2008) Tatiana Saldarriaga; V. Alberto Laguna-Torres; Juan Arrasco; Luis Sánchez Guillén; Juan Águila; Patricia Aguilar; Merly Sovero; Juan J. Pérez; Jane Adriana Vasconcelos Pacheco Rios; María Gamero
"Objetivo. Describir un brote de Influenza en dos bases militares en Tumbes, Perú. Material y métodos. Se utilizó la definición de caso de síndrome gripal del Ministerio de Salud en casos con menos de cinco días de inicio de síntomas. Se tomó hisopado nasal para la prueba rápida de Influenza (PRI) e hisopado faríngeo para aislamiento viral en tres líneas celulares (MDCK, VERO, LLCMK2). Para la genotipificación de Influenza B se usó un secuenciamiento parcial dela región de hemaglutinina de 898 pares de bases teniendo como base la cepa de la vacuna del 2007 (B/Florida/4/2006) y para el tipo A se analizó 958 pares de bases teniendo como referencia la cepa vacunal del 2007 (A/Brisbane/10/2007 (H3N2). Resultados. Se tomó 124 hisopados, 20 de la base militar (BM) # 1 y 104 de la BM # 2. La PRI identificó a 41 casos positivos: Flu B: 27, Flu A: 02, Flu: 12, con 62% de sensibilidad y 100% de especificidad. Finalmente, 66 casos fueron confirmados por cultivo celular, 54 Flu B y 12 Flu A. Los aislamientos de Tumbes fueron genéticamente similares con la cepa B/Texas/4/ 2006 (n=34) y A/Texas/91/2007 (H3N2)/ (n=7). Los síntomas más comunes fueron fiebre, cefalea,malestar general, tos, dolor de garganta, mialgias y rinorrea. Las medidas de control consistieron en el aislamiento de los casos identificados y el uso de mascarillas. Conclusiones. Se confirmó 66 casos de Influenza por cultivo celular. Los aislamientos tuvieron la mayor similitud genética con las cepas denominadas B/Texas/4/2006 y A/Texas/91/2007 (H3N2)."
Circulating Strains of Human Respiratory Syncytial Virus in Central and South America
(Public Library of Science, 2011) Merly Sovero; Josefina García; Tadeusz J. Kochel; V. Alberto Laguna-Torres; Jorge Gómez; Wilson Chicaiza; Melvin Barrantes; Félix Sánchez; Mirna Jimenez; Guillermo Comach
Human respiratory syncytial virus (HRSV) is a major cause of viral lower respiratory tract infections among infants and young children. HRSV strains vary genetically and antigenically and have been classified into two broad subgroups, A and B (HRSV-A and HRSV-B, respectively). To date, little is known about the circulating strains of HRSV in Latin America. We have evaluated the genetic diversity of 96 HRSV strains by sequencing a variable region of the G protein gene of isolates collected from 2007 to 2009 in Central and South America. Our results show the presence of the two antigenic subgroups of HRSV during this period with the majority belonging to the genotype HRSV-A2.
Detección de una cepa de influenza A (H1N1) pdm09 resistente al Oseltamivir en Perú
(National Institute of Health of Peru, 2014) Josefina García; Vidal Felices; Jorge Gómez; Elizabeth Gómez; V. Alberto Laguna-Torres
Immigration Status and HIV-risk Related Behaviors among Female Sex Workers in South America
(Springer Science+Business Media, 2007) Christian T. Bautista; Carlos Mosquera; Margarita Serra; Alberto Gianella; María Mercedes Ávila; V. Alberto Laguna-Torres; Jean K. Carr; Silvia M. Montano; José Luis Sánchez‐Ramos
Molecular characterization of adenovirus circulating in Central and South America during the 2006–2008 period
(Wiley, 2009) Josefina García; Merly Sovero; V. Alberto Laguna-Torres; Jorge Gómez; Wilson Chicaiza; Melvin Barrantes; Félix Sánchez; Mirna Jimenez; Guillermo Comach; Ivette Lorenzana
Our results indicate that 161(76%) adenoviruses belong to subgroup C, 45 (21%) to subgroup B and 7 (3%) to subtype E4.
Novel Strain of Andes Virus Associated with Fatal Human Infection, Central Bolivia
(Centers for Disease Control and Prevention, 2012) Cristhopher D. Cruz; Brett M. Forshey; Efraín Vallejo; Roberto Agudo; Jorge Vargas; David L. Blazes; Carolina Guevara; V. Alberto Laguna-Torres; Eric S. Halsey; Tadeusz J. Kochel
To better describe the genetic diversity of hantaviruses associated with human illness in South America, we screened blood samples from febrile patients in Chapare Province in central Bolivia during 2008-2009 for recent hantavirus infection. Hantavirus RNA was detected in 3 patients, including 1 who died. Partial RNA sequences of small and medium segments from the 3 patients were most closely related to Andes virus lineages but distinct (<90% nt identity) from reported strains. A survey for IgG against hantaviruses among residents of Chapare Province indicated that 12.2% of the population had past exposure to >1 hantaviruses; the highest prevalence was among agricultural workers. Because of the high level of human exposure to hantavirus strains and the severity of resulting disease, additional studies are warranted to determine the reservoirs, ecologic range, and public health effect of this novel strain of hantavirus.
Reemergence of Bolivian Hemorrhagic Fever, 2007–2008
(Centers for Disease Control and Prevention, 2009) Patricia V. Aguilar; Wilfredo Camargo; Jorge Vargas; Carolina Guevara; Yelin Roca; Vidal Felices; V. Alberto Laguna-Torres; Robert B. Tesh; Thomas G. Ksiazek; Tadeusz J. Kochel
age.In particular, suspected childhood TB patients without an identifiable TB contact and with normal immune status were subjected to further investigations.Multidisciplinary management, including enhanced laboratory diagnosis of atypical bony lesions in infants and children, is recommended for any suspected TB infection.Once BCGrelated infection is confirmed, medical treatment has to be consistent.