Browsing by Autor "Valeria Goyzueta"

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    Transformers meets neoantigen detection: a systematic literature review
    (2024) Vicente Machaca; Valeria Goyzueta; María Graciel Cruz; Erika Sejje; Luz Marina Pilco; Julio López; Yván Jesús Túpac Valdivia
    Cancer immunology offers a new alternative to traditional cancer treatments, such as radiotherapy and chemotherapy. One notable alternative is the development of personalized vaccines based on cancer neoantigens. Moreover, Transformers are considered a revolutionary development in artificial intelligence with a significant impact on natural language processing (NLP) tasks and have been utilized in proteomics studies in recent years. In this context, we conducted a systematic literature review to investigate how Transformers are applied in each stage of the neoantigen detection process. Additionally, we mapped current pipelines and examined the results of clinical trials involving cancer vaccines.