Browsing by Autor "Vanessa Pamela Salolin Vargas"

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    A comprehensive guide to conduct a systematic review and meta-analysis in medical research
    (Wolters Kluwer, 2025) Ernesto Calderón Martinez; Patricia E. Ghattas Hasbun; Vanessa Pamela Salolin Vargas; Oxiris Yexalén García‐González; Mariela D. Fermin Madera; Diego E. Rueda Capistrán; Thomas Campos Carmona; Camila Sánchez Cruz; C. Hooper
    Systematic reviews and meta-analyses are essential tools in medical research. Systematic reviews are a type of literature review that uses a systematic process to identify and assess all available literature on a specific research question. A meta-analysis is a statistical method of synthesizing the results of a systematic review by quantitatively combining data. The process begins with formulating a well-defined research question using frameworks. Comprehensive literature searches across multiple databases, including PubMed, Embase, and Cochrane, to ensure the inclusion of diverse studies. Tools like EndNote and Covidence streamline reference management and study selection, enhancing efficiency and accuracy. Quality assessment using tools like the Cochrane Risk of Bias Tool and Newcastle-Ottawa Scale is crucial to evaluate the methodological rigor. Data extraction, using standardized forms to ensure consistent information capture. Qualitative synthesis is one method that integrates the results of a systematic review focusing on textual data. Meta-analysis employs statistical software such as R and RevMan to compute effect sizes, confidence intervals, and assess heterogeneity. Visual representations, including forest and funnel plots, facilitate the interpretation of results. Challenges such as publication bias and heterogeneity are addressed using statistical methods like Egger regression and the trim-and-fill technique. Sensitivity analyses further validate the robustness of findings. Common errors, including data entry mistakes and inappropriate pooling, are mitigated through rigorous methodological adherence and critical self-evaluation. Meticulously conducted, systematic reviews and meta-analyses represent the pinnacle of the evidence hierarchy, driving advancements in medical research and practice.
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    Comparison of chemonucleolysis and discectomy in the management of lumbar disc herniation: a comprehensive systematic review and meta-analysis
    (Springer Science+Business Media, 2025) Cristian D. Mendieta; Fernando De Nigris Vasconcellos; Kevin Mamani-Julian; Priscilla Isabel Freeman; Fabricio Garcia-Torrico; Vanessa Pamela Salolin Vargas; Emanuela Binello
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    Evaluating Surgical Techniques for Craniosynostosis: A Systematic Review and Meta-Analysis on Endoscopic Approach Versus Open Surgery
    (Lippincott Williams & Wilkins, 2025) Fernando De Nigris Vasconcellos; Fabricio Garcia-Torrico; Victor Hugo Cardoso Betta; Giovanna Marques Dias Pedroso; Bryan T. Torres; Vanessa Pamela Salolin Vargas; M. Vilela; Sérgio Cavalheiro; Marcos Devanir Silva da Costa
    Endoscopic surgery offers a less invasive option with reduced transfusion needs, shorter hospital and ICU stays, and shorter surgery times. Both methods result in comparable long-term cranial shape outcomes, emphasizing individualized treatment. Further research is needed to explore long-term neurocognitive effects.
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    Stereotactic radiosurgery for recurrent/residual nonfunctioning pituitary adenoma: a single-arm systematic review and meta-analysis
    (Springer Science+Business Media, 2024) Fernando De Nigris Vasconcellos; M. Vilela; Fabricio Garcia Torrico; Marcos Agustín Scalise; Vanessa Pamela Salolin Vargas; Cristian D. Mendieta; Pavel Pichardo-Rojas; Maria Eduarda Almagro Rosi; Laura Tajara Fleury; Nádia Dantas de Brito Rebelo