Browsing by Autor "Vargas, Reynaldo"

Now showing 1 - 3 of 3

Avances en Proteómica
(RevActaNova., 2001) Pavisic, Davor; Argote, Gonzalo; Ordoñez, Soraya; Antezana, Oscar; Cary, Ariel; Antezana, Erick; Vargas, Reynaldo
Este artículo intenta brindar una introducción a la bioinformática, sus aplicaciones en la biología molecular y sus implicaciones en la medicina. Para esto, primeramente se define brevemente a los genes y su función en el proceso de formación de proteínas; estos dos términos ayudan a definir a la proteómica como el estudio de las proteínas expresadas por el genoma. El éxito de la proteómica depende de herramientas que permitan determinar la secuencia de aminoácidos que componen a una proteína. En este artículo se describen algunas técnicas bioinformáticas que actualmente se utilizan para la determinación de estas secuencias. La determinación de secuencias permite establecer una relación entre las proteínas y los genes que las codifican, conocimiento que puede servir para muchos propósitos diferentes. Entre los más importantes es establecer el papel que juegan los genes durante la enfermedad.
Feedforward Neural Networks for the Classification of Two-dimensional Polyacrylamide Gel Electrophoresis Images
(RevActaNova., 2001) Cary, Ariel; Pavisic, Davor; Vargas, Reynaldo
This article describes a method, using neural networks, for classifying two-dimensional polyacrylamide gel electrophoretograms, complex biomedical images that contain proteins separated from a biological sample. The classification aims at grouping images and identifying their most significant features. The gel image processing part is first summarized. The details on how the classification is accomplished using neural networks are then presented. After that, an experiment using real gels of rat cells is carried out, showing the successful implementation and application of this method. Finally, experimental results show that this neural network based method is more than 90% effective.
[Telemedicine in Bolivia: RAFT-Altiplano project, experiences, future prospects, and recommendations].
(2014) Vargas, Alejandro; Ugalde, Miguel; Vargas, Reynaldo; Narvaez, Ramiro; Geissbuhler, Antoine
OBJECTIVE: The objective of the RAFT-Altiplano project (RAFT: Réseau en Afrique Francophone pour la Télémédecine, or African Francophone Telemedicine Network) is to evaluate the viability, potential, and risks of implementing and developing a telemedicine network in the context of a developing country-specifically, the Altiplano region of Bolivia-to improve access to medical care and continuing education in a rural area. The activities described in this report took place between 2011 and 2013. METHODS: Digital telemedicine equipment was donated to the health centers and a Microsoft®-based platform capable of integration with other technologies (using standardized formats) was developed to manage documents and clinical content electronically. Health professionals were trained in teleconsultation and the teleconsultation workflow was designed. The tele-education system used is Dudal, which requires only a small bandwidth. RESULTS: After three years of implementation, an organized working structure of teleconsultation and tele-education tools, adapted to the Latin American context, is now in place and connections have been established with hospitals, institutions, and health centers. The project has improved access to specialized medical care in remote health centers and third-level hospitals in urban areas, and it has become the foundation for development of the national project "TeleSalud for Bolivia" promoted by the Ministry of Health, which involves use of the new Bolivian satellite, Túpac Katari. CONCLUSIONS: It is viable to develop and set up telemedicine tools to serve the population in remote regions of Bolivia when they are made available to government and municipal health institutions and communication between them and the health centers takes place in a coordinated manner. The sharing of experiences, challenges, and risks encountered is very useful in designing and implementing the telemedicine project "TeleSalud for Bolivia" on a national scale.