Browsing by Autor "William Gonzales"

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Caracterizacion de los factores de riesgo para osteoporosis en los pacientes del servicio de reumatologia del IAHULA Mérida 2016-2017
(2019) Luis Dulcey; Héctor Moreno; William Gonzales; Rodolfo Martheyn; Jonathan Pineda; José Sampayo; Diana Villamizar; A.O. Rosas; Vicente Martínez Rodríguez; Humberto Riera
Osteoporosis affects 20% of postmenopausal women in E.E.U.U. The lifetime risk of suffering a fracture after 50 years is 40% for women and 13% for men. In view of the fact that patients with rheumatological diseases present a higher risk for the development of osteoporosis, we set out to develop this study. Retrospective study aimed at determining the presence of risk factors in patients over 50 years of age who attend the IAHULA Rheumatology service in the period from 2016 to 2017. The main group of patients was the female gender and the ages between 50 and 65 years. The main rheumatological pathology was RA, followed by SLE, Arthrosis in 3 place and finally in the last cell other entities than those indicated. The 2 main risk factors for the development of osteoporosis were the use of steroids followed by obesity. The main type of osteoporosis of the 2 categories described was the non-serious one. Those with rheumatoid arthritis were the main group of rheumatological patients that was most associated with osteoporosis. 12% of patients with rheumatic disease and osteoporosis did not have appropriate therapy. There is a large percentage of patients with rheumatic disease who suffer from osteoporosis and as a special population, measures should be taken to prevent its appearance and to treat it in cases that suffer from it.
Estudio epidemiológico de hidatidosis comparando los test de ELISA IgE y Western Blot en población de cinco provincias de la Región Lima. 2015
(National University of San Marcos, 2018) Herman Vildózola; William Gonzales; Yrma Espinoza Blanco; Pedro Huapaya; Susana Jiménez; Mercedes Valenzuela Peña; Cristian Villar Huamán
ntroduction. Diagnosis of some zoonosis in different provinces from the Lima region, motivated on epidemiological investigation. Objective. To determine the prevalence of hydatidosis (echinococosis) in population from Lima region by ELISA IgE test compared with Western Blot. Methods. 560 sera samples were collected from people living in five provinces of Lima region: Canta (n=180), Huaral (n=55), Yauyos (n=133), Cajatambo (n=32) and Huaura (n=160). Antibodies IgE and IgG were detected by ELISA test and Western Blot respectively. Results. 39 samples were positives to ELISA IgE test (seroprevalence 6,96%) and 33 samples were positives to Western Blot IgG test (seroprevalence 5,89%), with light bands of 8 and 16 kDa. Positive samples proceeded from people of provinces of Canta, Yauyos and Huaura. Concordancy were determined between both tests (kappa index = 0,91). 50% (20/39) of positive subjects are from 25 to 60 years old, while less proportion of positives (1/39) were children under 5 years. Conclusions. ELISA IgE test can be used for the detection of positive person to anti Echinococcus spp. antibody, showing very high concordance with Westrn Blot IgG. Could be used in seroepidemiologic studies.
Reto terapéutico, los nuevos anticoagulantes orales en la práctica médica
(2019) Luis Dulcey; Raimondo Caltagironne; Héctor Moreno; C. Flores León; William Gonzales; Roldolfo Martheyn; Belkis Menoni; Jonathan Pineda; José Sampayo
Venezuelans Medicine faces difficult times because of the current crisis, however, it is not an excuse to be at the forefront of knowledge, and the topic of anticoagulation is one of the most important in recent times. At present we have new agents called new anticoagulants oral NACO, this generates a paradigm since some colleagues continue with the traditional anticoagulation schemes and others opt for these new agents, a conflict between the traditional and these new molecules for the facultative what daily treat millions of patients who receive these medications daily either as a treatment or to prevent the recurrence of thromboembolic events. It is then that it has been considered if the end of therapeutics with heparins or coumarins has come, this has generated a great controversy and there are many questions about this topic that have not been answered in the studies, it is for that reason that the extensive experience that has had with the traditional agents by multiple decades makes the doctors are cautious and do not dare to change the therapy, although everything points to that destination.