Browsing by Autor "Yunni Lara"

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Long-Standing International Cooperation in Parasitology Research: A Summary of 35 Years of Activities in the Bolivian Chaco
(Multidisciplinary Digital Publishing Institute, 2022) Simona Gabrielli; Fabio Macchioni; Michele Spinicci; Marianne Strohmeyer; Mimmo Roselli; Alessandra Nicoletti; Calogero Edoardo Cicero; Veronica Poma; David Rojo; Yunni Lara
The Bolivian Chaco is a semiarid region with a low population density, situated in the southeast part of the Plurinational State of Bolivia. Here, despite the improvements of the last 15 years, poverty remains high in rural areas, where social vulnerability is widespread. The Guaraní ethnic group often lives in isolated communities with a low standard of hygiene and sanitation. This epidemiological scenario favors the spread of transmissible diseases, including several parasitic infections belonging to the neglected tropical diseases (NTDs) group. In this area, a long-standing research activity, built upon the synergism between local and foreign institutions, has been established since the late 1980s and helps to fill in the knowledge gap about the epidemiology dynamics of soil-transmitted helminths, vector-borne parasites, and other parasitic diseases. A 35-year history of cooperation programs in parasitology research has contributed to informing local health authorities of the NTD burden in the Bolivian Chaco and, ultimately, supports local healthcare providers in the management of parasitic diseases.
Seroprevalence of Hepatitis A Virus, Hepatitis E Virus, and Helicobacter pylori in Rural Communities of the Bolivian Chaco, 2013
(American Society of Tropical Medicine and Hygiene, 2018) Irene Campolmi; Michele Spinicci; David Rojo Mayaregua; Herlan Gamboa Barahona; Antonia Mantella; Yunni Lara; Mimmo Roselli; Marianne Strohmeyer; Giampaolo Corti; Francesco Tolari
In the Bolivian Chaco, south-east of Bolivia, studies conducted over the past three decades reported hepatitis A virus (HAV) and Helicobacter pylori seroprevalences above 90% and 60%, respectively. Hepatitis E virus (HEV) prevalence was previously found to be 6-7% but is probably an underestimate because of the poor sensitivity of the assays used. In November 2013, we conducted a cross-sectional study of 263 healthy volunteers from two rural communities of the Bolivian Chaco, aiming to reassess HAV, HEV, and H. pylori seroprevalence 10-20 years following the previous surveys. Hepatitis A virus seroprevalence was 95%, with universal exposure after the first decade of life; HEV seroprevalence was considerably higher (31-35%) than that previously reported; H. pylori seroprevalence was 59%, with an age-dependent distribution. The high prevalence of these infections suggests that major efforts are still needed to reduce fecal-oral transmission and to improve human health in the Bolivian Chaco.
Seroprevalence of West Nile and dengue virus in the human population of the Bolivian Chaco
(Wiley, 2018) Alessandro Bartoloni; Maria Elena Remoli; Francesca Farchi; Lorenzo Zammarchi; Claudia Fortuna; Eleonora Benedetti; Maria Grazia Ciufolini; Fabio Macchioni; Patricia Rojas; Yunni Lara
To determine the seroprevalence of antibodies against dengue virus (DENV) and West Nile virus (WNV) in the human population of the Bolivian Chaco, we tested 256 inhabitants of two rural communities. The seroprevalence, confirmed by plaque reduction neutralization test, was 7.8% and 2.7% for DENV and WNV, respectively.
Trypanosoma cruzi infection in the human population of the Bolivian Chaco: four serosurveys over a 26-year period (1987-2013)
(Open Learning on Enteric Pathogens, 2020) Michele Spinicci; Simona Gabrielli; David Rojo; Herlan Gamboa; Fabio Macchioni; Antonia Mantella; Yunni Lara; Ana Liz Villagrán; Mimmo Roselli; Marianne Strohmeyer
T. cruzi transmission is still active and CD remains a concern throughout the Bolivian Chaco. More efforts are needed in order to achieve a sustainable interruption of vector-borne CD transmission in this area.