Ana Alberca PáramoDavid PadillaPedro Villarejo‐CamposH. Abdel-Hadi ÁlvarezLaureano Medina2026-03-222026-03-22202010.25132/raac.v112.n2.1436.eshttps://doi.org/10.25132/raac.v112.n2.1436.eshttps://andeanlibrary.org/handle/123456789/69188Nosocomial (hospital-acquired) diarrhea is usually caused by Clostridium difficile. On rare occasions it can cause acute respiratory distress syndrome (ARDS). Therefore, this condition should be suspected in order to make a diagnosis. Treatment is based on oral antibiotics. We report the case of a 66-yearold female patient with ARDS secondary to Clostridium difficile colitis after total pancreatectomy.enMedicineARDSClostridium difficileDiarrheaAcute respiratory distressAntibioticsClostridium Difficile ColitisRespiratory distressInternal medicinearticle