Ingrid Gaby Melgarejo PomarElfride Balanza ErquiciaLizeth Torrez ColmenaSergio Quisberth BarreraPilar Leina Suzaño Vargas2026-03-222026-03-22201810.17843/rpmesp.2017.344.2830https://doi.org/10.17843/rpmesp.2017.344.2830https://andeanlibrary.org/handle/123456789/55614Citaciones: 2The objective of this study was to determine the levels of malondialdehyde (MDA), an oxidative stress biomarker, in individuals living at high altitudes (3500-4200 m). This exploratory study evaluated 91 subjects from La Paz and El Alto using a questionnaire and clinical examination. MDA levels were measured using a colorimetric technique. Measures of central tendency, dispersion, and percentages were used to describe data, and the Mann-Whitney test and Kruskal-Wallis test were used to assess differences between the sexes, age groups, and altitudes. The median concentration of MDA was 4.1 μmol/L (RIC 2.4-5.4) and the highest concentration of MDA was found in individuals older than 40 years. The average MDA levels were higher than those found at sea level, a result we believe is due to the effect of hypoxia. However, there were no differences in the MDA levels between the sexes or age groups.enMalondialdehydeMann–Whitney U testHumanitiesOxidative stressarticle