Ramonet, MargaritaRamirez-Rodriguez, NelsonÁlvarez Chávez, FelipeArregui, María CBoldrini, GustavoBotero Osorio, VerónicaCuarterolo, MiriamGodoy, MarcelaMedina Monroy, Fernando AlonsoOropeza, GabrielaPérez Carusi, RosanaPérez Rodríguez, DianaReynoso-Zarzosa, Fátima AzerethCiocca, Mirta2026-03-242026-03-2420221668-3501PMID:3590095610.5546/aap.2022.eng.281https://doi.org/10.5546/aap.2022.eng.281https://andeanlibrary.org/handle/123456789/100964Vol. 120, No. 4, pp. 281-287Autoimmune hepatitis (AIH) is a chronic inflammatory condition of the liver characterized by a complex interaction among genetic factors, immune response to antigens present in hepatocytes, and immune regulation alterations. Its distribution is global and there is a female predominance. AIH is divided into 2 groups, depending on the type of serum autoantibodies detected. The most common presentation is acute hepatitis (40%), with non-specific symptoms, high aminotransferase levels, and hypergammaglobulinemia. Standard treatment consists of the administration of immunosuppressive drugs. It is a complex condition, often difficult to diagnose. If not managed adequately, the 5-year mortality rate may reach 75%.engtreatmentautoimmune hepatitispediatricsArtículo Científico Publicado