Ulises Rodríguez-WongUlises Rodríguez-MedinaG.R. Medina-Murillo2026-03-222026-03-22201810.1016/j.rgmx.2018.10.001https://doi.org/10.1016/j.rgmx.2018.10.001https://andeanlibrary.org/handle/123456789/50587Citaciones: 6Anal sphincter spasm contributes to the delay in surgical wound healing after hemorrhoidectomy. A prospective, experimental, randomized, double-blind trial was conducted on two groups of patients that underwent closed hemorrhoidectomy. There were 26 patients in each group. Group A received topical diltiazem in the anal region three times a day. Group B received a placebo. Cicatrization time was documented for 6 weeks through digital photography. Mean healing time for the group treated with diltiazem was 3.19 weeks (22.33±0.884 days) and 3.92 weeks (27.44±1.130 days) for the control group (p=0.012 95% CI). At week three, the wounds in 73.07% of the patients in the diltiazem group had healed, compared with 46.15% of the patients in the control group.esDiltiazemMedicinePlaceboSurgeryarticle