Valdivia, Ana CMollinedo, PatriciaVilaseca, AntonioSterner, Olov2026-03-232026-03-232009http://www.scielo.org.bo/scielo.php?script=sci_arttext&pid=S0250-54602009000200006&tlng=eshttps://andeanlibrary.org/handle/123456789/87815Vol. 26, No. 2Two new protocatechuic acid derivatives, arieianoic acid (1) and arieianol (2), were isolated from the aerial parts of Piper heterophyllum Ruíz & Pavon and their structures were determined by spectroscopic techniques. From 1, the semi-synthetic derivatives 3-8 were prepared. The antioxidant activity of the natural and semi-synthetic derivatives were evaluated using the DPPH assayTwo new protocatechuic acid derivatives, arieianoic acid (1) and arieianol (2), were isolated from the aerial parts of Piper heterophyllum Ruíz & Pavon and their structures were determined by spectroscopic techniques. From 1, the semi-synthetic derivatives 3-8 were prepared. The antioxidant activity of the natural and semi-synthetic derivatives were evaluated using the DPPH assayesPiper heterophyllumprenylated protocatechuic aciddiestertetraoldialdehydechromaneantioxidant activityArtículo Científico Publicado